Research Scientist - College of Medicine | Surgery

The Ohio State University College of Medicine and the Wexner Medical Center seek Bioinformatics Scientist to join the Department of Surgery.

Position Overview

The Division of Surgical Oncology, Department of Surgery at The Ohio State University Wexner Medical Center is seeking an exceptional Bioinformatics Scientist to support and advance translational and clinical research programs, with a particular focus on cancer genomics and high-dimensional data analysis. The successful candidate will work closely with multidisciplinary teams of clinicians, basic scientists, and data scientists to analyze and interpret large-scale datasets, including next-generation sequencing (NGS), transcriptomics, epigenomics, and other multi-omic platforms.

This individual will play a central role in the development, implementation, and optimization of bioinformatics pipelines; integration of clinical and molecular datasets; and generation of insights that inform biomarker discovery, therapeutic targeting, and clinical trial design. The position is ideal for candidates with strong computational expertise, scientific curiosity, and a collaborative mindset.

The Bioinformatics Scientist will contribute to ongoing institutional initiatives including biorepository efforts, precision oncology programs, and investigator-initiated clinical trials. Opportunities exist for independent and collaborative research, authorship, and grant development.

Key Responsibilities

• Develop, implement, and maintain bioinformatics pipelines for analysis of high-throughput sequencing data (e.g., DNA-seq, RNA-seq, single-cell sequencing, spatial transcriptomics)
• Perform integrative analyses of genomic, transcriptomic, and clinical datasets
• Collaborate with clinical and laboratory investigators to design studies and interpret results
• Support biomarker discovery and molecular subtyping efforts
• Contribute to grant applications, manuscripts, and presentations
• Ensure reproducibility and documentation of computational workflows
• Maintain data integrity and compliance with institutional and regulatory standards
• Provide mentorship and training to trainees and research staff as appropriate

Requirements

• PhD in Bioinformatics, Computational Biology, Computer Science, Biostatistics, or a related field
• Demonstrated experience with high-throughput sequencing data analysis
• Proficiency in programming languages (e.g., Python, R) and bioinformatics tools
• Experience with genomic data platforms (e.g., Illumina, 10x Genomics)
• Familiarity with statistical modeling and machine learning approaches
• Strong record of collaborative research and/or publications
• Excellent communication and organizational skills
• Experience with cancer genomics and translational oncology research
• Experience integrating clinical and molecular datasets
• Familiarity with cloud computing environments and high-performance computing clusters