"Research Specialist B"

Research Specialist B

Job Description Summary

The laboratory studies breast and ovarian cancer with the goal of predicting response to therapy and developing new therapies (test new drug candidates). We use cell culture and mouse models and organoids to probe the cellular, molecular pathways important for breast/ovarian cancer response.

The job will support research projects by conducting experiments or studies, collecting and analyzing data, and maintaining research tools, equipment, or project resources. Contributes to study design, documentation, and reporting, and collaborates with investigators and staff to ensure projects are carried out effectively and in compliance with established protocols.

Job Description

General Job Responsibilities

• Conduct laboratory research, troubleshoot problems, analyze data, design new research experiments along with research publications, and prepare presentations.
• Participate in lab management and help support lab set up and operations, oversee ordering, organization and maintenance of reagents, equipment, and protocols.
• Train and supervise other lab members as needed, provide scientific and technical expertise and guidance for other ongoing projects
• Other duties and responsibilities as assigned
• Position is Contingent Upon Grant Funding

We are looking for an energetic and talented additional team member to help us with the goal of finding a cure for breast cancer. The laboratory studies breast and ovarian cancer with the goal of predicting response to therapy and developing new therapies (test new drug candidates). We use cell culture and mouse models and organoids to probe the cellular, molecular pathways important for breast/ovarian cancer response.

This research specialist will be expected to manage a unique scientific project with input from the PI and group. They will be expected to maintain detailed records and produce methods and figures. They will be expected to master a few bench techniques or animal modeling work in the patient derived xenograft core and be available for training new lab members and students in those techniques. We hope to involve them in our new organoid efforts. They will not be expected to write manuscripts or present at national meetings but this is an option if desired.

Specific Job Responsibilities

The research specialist will be responsible for conducting experiments related to the molecular basis of cancer and assist with translational experiments that will lead to new therapies and clinical trials.

Duties will include contributing to general laboratory organization and inventories (as part of a team doing this).

We have considerable need for someone who can do autoradiography to help us with both new radiotracer evaluation and a planned radiotherapy program.

The research specialist will assist in the conduct of experiments using both human and animal model systems, including providing and documenting animal care.

The research specialist will assist lab members in organizing the efforts of undergraduate assistants, participate in regularly scheduled scientific discussions, and assist with the analysis and interpretation of experimental results.

The research specialist will closely collaborate with senior lab members and the PI to assist with molecular and genetic experiments, including reagent preparation, cell culture, RNA and DNA extractions, PCR, qPCR, and second and third generation genetic sequencing.

The nature of this position provides considerable opportunity for motivated candidates to develop and master complex scientific approaches that are broadly applicable to scientific research.

Communication skills: maintaining accurate, detailed notes; and conveying research findings at group lab meetings is essential.

Responsibility Breakdown: -- Assist with the patient derived xenograft program - autoradiography - Place orders, manage inventories, and organize deliveries-- Maintain laboratory organization - Perform independent experiments-- Perform additional duties as assigned.

Qualifications

• Bachelor of Science and 1 to 2 years of experience or equivalent combination of education and experience is required.

Job Location

Philadelphia, Pennsylvania

Department / School

Perelman School of Medicine