"Research Technician ? Fischer Lab"

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world-renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

The Fischer Lab at Dana-Farber Cancer Institute is a Structural and Chemical Biology Lab that combines a broad range of laboratory techniques to study the pathways and protein complexes involved in the regulation of protein homeostasis often associated with human diseases, including cancer. Using our knowledge of the cellular degradation machinery, we use structure and computational guided approaches to develop and test new molecules that hijack the ubiquitin proteasome system for targeted protein degradation. Combining fundamental mechanistic insights with translational chemical biology research, we are pioneering new therapeutic avenues.

The Fischer lab (https://fischerlab.dana-farber.org/) seeks a highly motivated individual to join the team as a RESEARCH TECHNICIAN, who will employ mass spectrometry-based technologies to assess the cellular proteome in response to external stimuli. This individual will be an important member of our core team and will work with technicians, scientists, postdocs and students on a variety of different research projects focused on targeted protein degradation as a novel therapeutic modality.

Responsibilities:

• Mammalian cell line management and ability to perform drug treatments and prepare samples from tissues and cells
• Prepares lab reagents and media
• Performs mass spectrometry sample preparation
• Operation and maintenance of standard lab equipment including HPLC’s, mass spectrometers
• Analyzes experimental data and interpret results to write reports, presentations, grant and publication preparation
• Maintains detailed notebook of all work-related activities
• Maintains and orders laboratory supplies
• Communicates with purchasing and may be responsible for negotiating with vendors
• Collaborates with other lab members for the development, modification and improvement of standard operating procedures

MINIMUM JOB QUALIFICATIONS:

• Bachelor's Degree required with a major in biology or chemistry preferred
• A knowledge of information and techniques related to biology, chemistry or medicine is preferred
• Understanding of statistical and computational methods is desirable
• Must have close attention to detail and consistent work habits
• Must have good time management
• Ability to work in a collaborative and team environment
• Excellent oral and written capabilities
• Experience with R, MATLAB, or python and general computational abilities is preferred

SUPERVISORY RESPONSIBILITIES: No supervisory responsibilities. Normally receives detailed instructions on all work.

PATIENT CONTACT: None

Pay Transparency Statement: The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate’s relevant experience, skills and qualifications. $47,500.00 - $51,300.00