City of Hope stands as a beacon in the fight against cancer, diabetes, and other life-threatening diseases, offering transformative career opportunities in research, healthcare, and administration. Located primarily in Duarte, California, with key operations and positions in nearby Monrovia, this prestigious institution attracts top talent worldwide. Jobs at City of Hope span from cutting-edge laboratory research to patient-centered clinical roles, making it an ideal destination for those passionate about advancing medical science.
What defines a job at City of Hope? These positions contribute directly to groundbreaking discoveries, such as novel immunotherapies and personalized medicine approaches. With a growing national system that includes multiple Southern California locations, including Monrovia, professionals find roles in dynamic environments that blend innovation with compassionate care. Whether you're a recent PhD graduate eyeing postdoc jobs or an experienced clinician, City of Hope provides pathways to impactful work.
The institution's commitment to excellence is evident in its over 100 years of service, producing Nobel laureates and numerous FDA-approved therapies. In Monrovia specifically, opportunities often focus on support roles like phlebotomy and medical assisting that underpin larger research efforts, alongside research technician positions.
Founded in 1913 as a tuberculosis sanatorium, City of Hope evolved into a comprehensive cancer center by the mid-20th century. Today, it encompasses the City of Hope National Medical Center, Beckman Research Institute, and Irell & Manella Graduate School of Biological Sciences. This evolution mirrors the expansion of jobs at City of Hope, from early clinical staff to today's multidisciplinary teams tackling complex diseases.
Key milestones include the establishment of the Beckman Research Institute in 1984, which now hosts hundreds of researchers. In Monrovia, facilities support this mission through specialized labs and outpatient services. Understanding this history helps job seekers appreciate the institution's culture of resilience and innovation, where careers often lead to lifelong contributions in biomedicine.
City of Hope offers diverse roles tailored to various expertise levels. Research positions dominate, including staff scientists, research associates, and technicians working on immunotherapy and genomics. Clinical jobs, such as licensed vocational nurses (LVNs), medical assistants, and phlebotomists, are plentiful in Monrovia, ensuring direct patient impact.
Administrative and support roles, like patient access representatives, complement these. For academics, faculty-like positions in the graduate school involve teaching and mentoring. Explore broader university job types to see how these align with higher education careers. Recent listings highlight laboratory technical assistants with rotating shifts, emphasizing the hands-on nature of Monrovia-based work.
Academic credentials form the foundation for most positions. Research roles typically demand a PhD in fields like molecular biology, biochemistry, or oncology. MDs are preferred for translational research bridging lab and clinic. Entry-level lab tech jobs may require a bachelor's in biology or related sciences, while clinical positions like LVNs need state licensure and associate degrees.
For advanced roles, such as principal investigators, a proven track record with a doctoral degree is essential. The Irell & Manella Graduate School offers PhD programs, creating internal pipelines for jobs at City of Hope.
City of Hope's research emphasizes immunotherapy, hematopoietic stem cell transplantation, and diabetes prevention. Expertise in CRISPR gene editing, flow cytometry, or bioinformatics is crucial for competitive applications. Monrovia roles often support these through sample processing and data collection for larger Duarte-based projects.
Candidates should align their skills with ongoing initiatives, like proton therapy advancements or AI-driven drug discovery, to stand out.
Preferred experience includes peer-reviewed publications, grant funding from NIH or similar, and prior lab management. For clinical research, familiarity with Good Clinical Practice (GCP) guidelines is key.
Essential skills encompass:
Soft competencies like adaptability in fast-paced settings and ethical research conduct are equally valued.
Beckman Research Institute: City of Hope's dedicated arm for basic, translational, and clinical research, housing state-of-the-art facilities for disease modeling and therapy development.
Immunotherapy: A treatment approach harnessing the immune system to fight cancer, a core focus at City of Hope with CAR-T cell innovations.
Postdoctoral Fellowship: A temporary research position for recent PhDs to gain advanced training, often lasting 2-5 years, leading to independent faculty roles.
Translational Research: The process of turning laboratory discoveries into clinical applications, bridging bench-to-bedside at City of Hope.
The application process begins with searching open positions on City of Hope's careers site, submitting a tailored CV, cover letter, and references. Interviews often include technical panels and presentations.
Actionable tips:
For Monrovia roles, emphasize local availability and flexibility for shift work.
City of Hope champions diversity through the Excellence in Mentoring Program, targeting underrepresented minorities in STEM, and the Women's Initiative for leadership development. They host affinity groups for LGBTQ+ and veterans, ensuring equitable opportunities. In 2025, over 40% of new hires were from diverse backgrounds, reflecting commitment to inclusive excellence in research teams.
Work-life balance at City of Hope is supported by hybrid options for researchers, 4/10 shift schedules for clinical staff, and robust wellness programs including yoga and mental health resources. Benefits feature tuition assistance for further education, on-site fitness centers, and family leave policies.
Campus life in Monrovia offers proximity to urban amenities in sunny Southern California, with team-building events and seminars fostering community. Employees rave about the collaborative vibe, where professional growth aligns with personal well-being, as noted in Glassdoor reviews averaging 4 stars.
Ready to join this mission-driven organization? Browse higher ed jobs, refine your profile with higher ed career advice, search university jobs, or post your resume today. For research enthusiasts, check research jobs and postdoctoral success tips. City of Hope awaits those ready to turn hope into reality.
With ongoing expansions, now is prime time for jobs at City of Hope in Monrovia, blending academic rigor with real-world impact.
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