Rate My Professor Angela Bruzzaniti

Angela Bruzzaniti, PhD, is Professor in the Department of Biomedical Sciences and Comprehensive Care at the Indiana University School of Dentistry, where she also serves as Director of the PhD Program and Research Development and Director of Dental Student Research. She holds an adjunct appointment as Professor in the Department of Anatomy, Cell Biology, and Physiology at the Indiana University School of Medicine. Dr. Bruzzaniti earned her PhD from the University of Melbourne in 1997 and completed postdoctoral fellowships at Yale University School of Medicine and Johns Hopkins University. She joined the Indiana University School of Dentistry faculty in 2008, advancing to her current professorial rank. In her teaching roles, she delivers courses on musculoskeletal biology and molecular cell biology, while actively mentoring DDS students, graduate students, and postdoctoral researchers in their projects.

Dr. Bruzzaniti's federally funded research program centers on cellular mechanisms underlying bone remodeling, with a focus on preventing bone loss and promoting bone growth. Her scholarly interests encompass cell biology, bone biology, and skeletal physiology, as reflected in her Google Scholar profile with over 2,500 citations. Notable publications include 'The Rho-GEF Kalirin regulates bone mass and the function of osteocytes and osteoclasts' (Bone, 2013), 'Pyk2 and Megakaryocytes Regulate Osteoblast Differentiation and Matrix Mineralization' (Journal of Cellular Biochemistry, 2015), 'Osteocyte-Derived CaMKK2 Regulates Osteoclasts and Bone Mass' (International Journal of Molecular Sciences, 2023), 'High Bone Mass in Mice Lacking Cx37 Because of Defective Osteoclastogenesis' (Journal of Biological Chemistry, 2005), and 'Reversal of Bone Loss in Mice by Nongenotropic Signaling of Parathyroid Hormone' (Science, 2002). She contributes to major NIH initiatives, including a Practice-Based Research Integrating Multidisciplinary Experiences in Dental, Oral, and Craniofacial Research (PRIMED) grant and projects representing one of the largest awards in the dental school's history. Through her leadership in PhD training and student research, Dr. Bruzzaniti fosters the next generation of oral health researchers and faculty.