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Professor Anthony Green is a Professor in Organic Chemistry in the Department of Chemistry at the University of Manchester. He earned an MSci from the University of Nottingham and a PhD in synthetic organic chemistry from the University of Manchester under Professor E. J. Thomas. He conducted postdoctoral research with Professors Nicholas Turner and Sabine Flitsch at the Manchester Institute of Biotechnology and with Professor Donald Hilvert at ETH Zurich. Green launched his independent career in 2016 at the University of Manchester as a BBSRC David Phillips Fellow and Lecturer in Organic and Biological Chemistry. He advanced to Reader in 2020 and currently holds leadership roles as Director of the Manchester Institute of Biotechnology since 2024, Director of the International Centre for Enzyme Design since 2024, and Director of CoEBio3 since 2022.
Green's research focuses on enzyme design, directed evolution, genetic code expansion, and biocatalysis to engineer catalysts for non-natural reactions, supporting sustainable manufacturing in pharmaceuticals, agrochemicals, plastics recycling, and biofuels. His innovations include reengineering cytidine deaminase for molnupiravir production, a COVID-19 antiviral; enzymes for lenacapavir, an HIV drug; thermostable PET depolymerases; and visible light-powered photoenzymes for selective cycloadditions and energy transfer. Key publications encompass 'Engineered enzymes for enantioselective nucleophilic aromatic substitutions' (Nature, 2025), 'Efficient and Selective Energy Transfer Photoenzymes Powered by Visible Light' (Nature Chemistry, 2025), 'Biocatalytic Activation of Sulfur Heteroaromatics Facilitates Dearomatizing Cross-Couplings to Set Stereogenic Centers or Axes' (Journal of the American Chemical Society, 2025), and 'Directed Evolution of an Efficient Polycarbonate Depolymerase With Exceptional Operational Stability' (Angewandte Chemie International Edition, 2026). His accolades include the Blavatnik Awards for Young Scientists Chemical Sciences Laureate (2024), Harrison-Meldola Memorial Prize (2020), ERC Consolidator Grant (2023), ERC Starting Grant (2017), Outstanding Achievement Award from the University of Manchester (2017), and EPSRC Doctoral Prize (2009). Green serves as an academic expert for the Biotechnology and Biological Sciences Research Council since 2018 and the American Chemical Society since 2016.
University of Manchester scientists develop biocatalytic method for Lenacapavir production, cutting costs and waste to boost global HIV prevention access.
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