Rate My Professor Brent Nannenga

Nannenga’s research focuses on method development and new applications of structural biology and protein engineering, utilizing MicroED and cryo-EM for high-resolution structure determination of biomolecules and materials. His investigations encompass protein-inorganic interfaces, ferritin iron uptake and oxidation mechanisms, metal-organic frameworks, covalent organic frameworks, photosynthetic systems in bacteria, and amyloid beta fragments. He has authored or co-authored numerous influential publications, including "Structure of the toxic core of α-synuclein from invisible crystals" (Nature, 2015), "Three-dimensional electron crystallography of protein microcrystals" (eLife, 2013), "High-resolution structure determination by continuous-rotation data collection in MicroED" (Nature Methods, 2014), "High thermodynamic stability of parametrically designed helical bundles" (Science, 2014), "The cryo-EM method microcrystal electron diffraction (MicroED)" (Nature Methods, 2019), and "Structure of catalase determined by MicroED" (eLife, 2014). These works have collectively amassed thousands of citations, underscoring his impact in structural biology, nanotechnology, and biotechnology. Nannenga’s innovations in MicroED have facilitated structural insights across diverse fields, from pharmaceuticals to photovoltaics. His contributions have earned him the NSF CAREER Award, Air Force Office of Scientific Research Young Investigator Award, 2020 Burton Medal from the Microscopy Society of America, and 2022 Margaret C. Etter Early Career Award from the American Crystallographic Association.