Rate My Professor Connie Jackaman

Dr. Connie Jackaman is a Senior Lecturer in Immunology and Program Lead for Inflammation in the Curtin Medical School, Faculty of Health Sciences at Curtin University. She is affiliated with the Curtin Health Innovation Research Institute (CHIRI) and Curtin Medical Research Institute (Curtin MRI), where she leads the Immunoageing Lab. Her research focuses on age-associated alterations in immune responses, particularly the roles of myeloid cells such as macrophages and neutrophils in cancer, inflammation, infectious diseases, and wound healing. Utilizing murine models of mesothelioma, Dr. Jackaman investigates tumor-induced modulation of dendritic cells, accumulation of suppressive regulatory T cells, and the potential of therapies like checkpoint blockade and cytokine-armed viruses to enhance anti-tumor immunity in the elderly. Her studies also examine aged neutrophils in lymphoid tissues, monocyte and macrophage accumulation during influenza infection, and inflammation's impact on muscle and brain in aging.

Dr. Jackaman has authored numerous peer-reviewed publications with significant impact, including 'Aging and cancer: The role of macrophages and neutrophils' (2017, cited over 290 times), 'Murine mesothelioma induces locally-proliferating IL-10+TNF-suppressive but IFNγ+PD-L1^neg regulatory T cells' (2016), 'Cytokine-armed vaccinia virus infects the mesothelioma tumor and specifically modifies tumor immune responses' (2010), 'Aging Leads to Increased Monocytes and Macrophages Accumulation in the Lungs during Influenza Infection' (2022), 'Lipid-laden partially-activated plasmacytoid and CD4−CD8α^lo dendritic cells accumulate in murine mesothelioma' (2014), and 'Modulation of dendritic cell and T cell cross-talk during aging: The potential role of checkpoint inhibitory molecules' (2017). Her Google Scholar profile indicates an h-index of 27 and nearly 2,000 citations. She received the 2014 Curtin Research Award for Excellence in Research Support and held an Early Career Development Fellowship at CHIRI. Dr. Jackaman contributes to NHMRC-funded projects on age-related inflammation and serves as a supervisor for PhD students. She has been involved with the Australasian Society for Immunology as a WA Councillor.