Rate My Professor David Giedroc

David P. Giedroc is the Distinguished Professor and Lilly Chemistry Alumni Professor in the Department of Chemistry at Indiana University Bloomington. He earned his B.S. in Biochemistry from the Pennsylvania State University in 1980 and his Ph.D. in Biochemistry from the Vanderbilt University School of Medicine in 1984. Following his doctoral work, he was an NIH postdoctoral fellow with Walter Chazin at the Scripps Research Institute from 1984 to 1987. Giedroc then served as an Established Investigator of the American Heart Association at the University of Utah School of Medicine from 1987 to 1993, and as Professor and Head of Biological NMR in the Department of Biochemistry at Texas A&M University from 1993 to 2007. He joined the Department of Chemistry at Indiana University Bloomington in 2007 as Professor of Chemistry and served as Department Chair from 2013 to 2018.

Giedroc's research focuses on the biophysics of infectious disease, particularly the mechanisms of metal ion sensing, transport, and homeostasis in bacterial pathogens that contribute to virulence and host defense. His laboratory has elucidated protein allostery in metalloregulatory proteins of the CsoR/RcnR family, bacterial persulfide sensors that confer protection against hydrogen sulfide toxicity (Nature Chemical Biology, 2020), and the first dedicated cellular zinc chaperone (Cell, 2022). Key publications include "Coordination Chemistry of Bacterial Metal Transport and Sensing" (Chemical Reviews, 2009), "Insights into Protein Allostery in the CsoR/RcnR Family of Transcriptional Reporters" (2013), and "Multi-metal Restriction by Calprotectin Impacts De Novo Pyrimidine Synthesis in Uropathogenic E. coli" (Cell Chemical Biology, 2019). His scholarly impact is evidenced by extensive citations and contributions to bioinorganic chemistry and microbiology. Giedroc has received the Distinguished Professor designation from Indiana University in 2020, the Trustees Teaching Award in 2021, and the 2015 Diversity Catalyst Lecturer award from OXIDE. He co-directs the Quantitative and Chemical Biology Graduate Program.