Rate My Professor David Giedroc

Giedroc's research focuses on the biophysics of infectious disease, particularly the mechanisms of metal ion sensing, transport, and homeostasis in bacterial pathogens that contribute to virulence and host defense. His laboratory has elucidated protein allostery in metalloregulatory proteins of the CsoR/RcnR family, bacterial persulfide sensors that confer protection against hydrogen sulfide toxicity (Nature Chemical Biology, 2020), and the first dedicated cellular zinc chaperone (Cell, 2022). Key publications include "Coordination Chemistry of Bacterial Metal Transport and Sensing" (Chemical Reviews, 2009), "Insights into Protein Allostery in the CsoR/RcnR Family of Transcriptional Reporters" (2013), and "Multi-metal Restriction by Calprotectin Impacts De Novo Pyrimidine Synthesis in Uropathogenic E. coli" (Cell Chemical Biology, 2019). His scholarly impact is evidenced by extensive citations and contributions to bioinorganic chemistry and microbiology. Giedroc has received the Distinguished Professor designation from Indiana University in 2020, the Trustees Teaching Award in 2021, and the 2015 Diversity Catalyst Lecturer award from OXIDE. He co-directs the Quantitative and Chemical Biology Graduate Program.