Rate My Professor Deepak Srivastava

His research investigates synaptic biology in health and disease, focusing on molecular mechanisms regulating glutamatergic synapses, the influence of genetic risk factors on synaptic function in neurodevelopmental and psychiatric disorders including schizophrenia, autism spectrum disorders, intellectual disability, and synaptic deficits in Alzheimer’s disease. Employing patient-derived induced pluripotent stem cells, advanced cellular imaging, primary cell cultures, and animal models, his lab examines synaptic protein organization and synapse remodelling for neural circuitry refinement. Key publications include 'Electrophysiological development and functional plasticity in dissociated human cerebral organoids across multiple cell lines' (Cell Reports Methods, 2026), 'Polygenic scores for autism are associated with reduced neurite density in adults and children from the general population' (Molecular Psychiatry, 2025), 'Integrating human endogenous retroviruses into transcriptome-wide association studies highlights novel risk factors for major psychiatric conditions' (Nature Communications, 2024), 'Interferon-γ signaling in human iPSC-derived neurons recapitulates neurodevelopmental disorder phenotypes' (Science Advances, 2020), and 'Psychosis risk candidate ZNF804A localizes to synapses and regulates neurite formation and dendritic spine structure' (Biological Psychiatry, 2017). He edits Molecular and Cellular Neurosciences since 2021 and Frontiers in Molecular Neuroscience since 2018, and leads grants such as the MRC Human Functional Genomics initiative.