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Rate My Professor Dipali Sashital

Iowa State University Foundation

Ratings & reviews

5.04/23/2026

Encourages students to think independently.

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About Dipali

Dipali Sashital is the Roy J. Carver Professor of Biochemistry, Biophysics, and Molecular Biology in the Roy J. Carver Department of Biochemistry, Biophysics, and Molecular Biology at Iowa State University. A leader in Biology research, she investigates the molecular mechanisms underlying the function of RNA-protein complexes involved in gene regulation and genome maintenance. Her lab employs biochemical, structural, including cryo-electron microscopy, and cellular tools to study these complexes, with a particular emphasis on bacterial and archaeal CRISPR-Cas immune systems. These systems use guide RNAs and effector proteins to target and destroy foreign nucleic acids from bacteriophages and plasmids, while avoiding off-target effects. Sashital's work elucidates the interference mechanisms and activation processes during immune responses, contributing to advancements in precise gene editing technologies with applications in human health and agriculture.

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