Rate My Professor Esteban Marcellin

Professor Esteban Marcellin is a Professor and Group Leader of the Marcellin Group at the Australian Institute for Bioengineering and Nanotechnology, University of Queensland. He holds a Bachelor of Chemical Engineering with Honours from Universidad Iberoamericana and a Doctor of Philosophy from the University of Queensland, where he completed his PhD between 2006 and 2010. Marcellin serves as a Professorial Research Fellow affiliated with the School of Chemical Engineering. His research centers on advanced biomanufacturing through systems and synthetic biology, utilizing high-throughput omics technologies including genomics, transcriptomics, proteomics, and metabolomics, integrated with mathematical models to engineer microbial and mammalian production strains. A primary focus is gas fermentation with acetogens such as Clostridium autoethanogenum to convert waste gases like CO and CO2 into sustainable fuels, chemicals, proteins, and other commodities, promoting a circular bioeconomy.

Marcellin collaborates extensively with industry leaders including LanzaTech, Amyris, Zoetis, Dow, CSL, and Thermo Fisher Scientific to enhance bioprocess yields and productivity. Key publications include 'Microbial propionic acid production' (2017), 'Low carbon fuels and commodity chemicals from waste gases–systematic approach to understand energy metabolism in a model acetogen' (2016), 'Maintenance of ATP homeostasis triggers metabolic shifts in gas-fermenting acetogens' (2017), 'Enhancing CO2-valorization using Clostridium autoethanogenum for sustainable fuel and chemicals production' (2020), 'Absolute Proteome Quantification in the Gas-Fermenting Acetogen Clostridium autoethanogenum' (2022), and 'Redox controls metabolic robustness in the gas-fermenting acetogen Clostridium autoethanogenum' (2020, PNAS). He leads major projects such as the Queensland Strain Factory (2020–2027), BiG Chemicals (2015–2018), Biopharmaceuticals 4.0 (2023–2026), and contributes to the UQ Biosustainability Hub, driving innovations in sustainable bioproduction.