Encourages critical thinking and analysis.
Makes learning feel effortless and fun.
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Feng Tang is an Assistant Professor in the Department of Chemistry at the University of Florida. He received his B.S. degree in 2014 and Ph.D. degree in 2020 from Wuhan University. Following his doctoral studies, he conducted postdoctoral research at the University of California, Riverside from 2020 to 2024. Tang's research focuses on the development of innovative platforms for the multidimensional profiling of DNA damage within the human genome. By integrating high-throughput sequencing technologies, mass spectrometry, chemical biology approaches, machine learning, and bioinformatics, his laboratory investigates the chemical structures, abundances, genomic locations, and time-resolved dynamics of various DNA lesions as well as the associated repair proteins. This comprehensive approach enables the study of DNA damage responses in contexts such as cancer biology, environmental toxicology, and the evaluation of off-target effects in genome editing technologies. His work also explores implications for tumorigenesis, neurodegeneration, immune dysfunction, and aging.
In recognition of his contributions, Feng Tang has been awarded the K99/R00 NIH Pathway to Independence Award spanning 2023 to 2028, the CASMS Young Investigator Award in 2025, and the UCR Postdoc Awards for Excellence in 2024. His notable publications include "DNA Polymerase κ Participates in Early S-Phase DNA Replication in Human Cells" published in Proceedings of the National Academy of Sciences in 2024, "Polymerase η Recruits DHX9 Helicase to Promote Replication across Guanine Quadruplex Structures" in the Journal of the American Chemical Society in 2022, "DNA-Protein Cross-Linking Sequencing for Genome-Wide Mapping of Thymidine Glycol" in the Journal of the American Chemical Society in 2022, "m1A in CAG repeat RNA binds to TDP-43 and induces neurodegeneration" in 2023, and "Formation and removal of 1,N6-dimethyladenosine in mammalian transfer RNA" in 2022. Tang contributes to the academic community as a member of the Graduate Admissions Committee for the Analytical Division since 2025, an Early Career Advisory Board Member for Chemical Research in Toxicology starting in 2025, and an Editorial Board Member for Health and Metabolism since 2024.
