Encourages students to think outside the box.
Jacqui Lee serves as a Senior Research Technician in the Department of Medicine at the University of Otago, Christchurch campus. She is affiliated with the Christchurch Heart Institute, where she works as part of the technical staff in the Translational Biodiscovery Laboratory. This laboratory specializes in translational biodiscovery research, focusing on the development of novel biomarker assays for the diagnosis and prognosis of diseases, particularly cardiovascular conditions. The team utilizes advanced technologies including radioimmunoassay (RIA), enzyme-linked immunosorbent assay (ELISA), Luminex, Roche Cobas, and Brahms Kryptor platforms, along with facilities for cell culture and isolated heart studies. The laboratory complies with FDA requirements and ISO15189 standards, and collaborates on commercial studies with companies such as Roche, Abbott, Sphingotec, and ThermoFisher. Assays developed in the laboratory include those for atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), N-terminal proBNP (NT-proBNP), C-type natriuretic peptide (CNP), neutral endopeptidase (NEP), adrenomedullin, angiotensin II, angiotensin converting enzyme (ACE), plasma renin activity, arginine vasopressin, ACTH, cortisol, aldosterone, endothelin, cGMP, cAMP, catecholamines, ghrelin peptides, and signal peptide fragments.
Jacqui Lee has contributed to peer-reviewed publications in the field of cardiovascular medicine. She is a co-author on the paper 'CNP Signal Peptide in Patients with Cardiovascular Disease,' published in Frontiers in Cardiovascular Medicine in 2015, which examined circulating levels of CNP signal peptide in patients with acute coronary syndrome, chronic heart failure, and other cardiovascular conditions. Her technical expertise has also been acknowledged in additional studies, such as those investigating natriuretic peptides and receptor activity, and biochemical biomarker responses in marine organisms. These contributions support ongoing clinical and translational research efforts at the Christchurch Heart Institute within the Division of Health Sciences.

Photo by Osarugue Igbinoba on Unsplash
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