Rate My Professor Jed Lempe

Dr. Jed Lampe is an Associate Professor in the Department of Pharmaceutical Sciences at the University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Anschutz Medical Campus. He holds a BS in Biological Sciences from Walla Walla University, an MS in Microbiology from Idaho State University, a PhD in Medicinal Chemistry from the University of Washington, and completed a Postdoctoral Fellowship in Pharmaceutical Chemistry at the University of California, San Francisco. As an R01-funded principal investigator, educator, and scientific leader in the ADME/DMPK field, Dr. Lampe applies bioanalytical, biophysical, and computational techniques to study drug metabolism and disposition, with a focus on special populations such as neonates and developing infants. His research explores ligand binding dynamics and enzyme function in cytochrome P450 enzymes, employing pioneering two-dimensional NMR techniques with site-specifically incorporated unnatural amino acids.

Dr. Lampe's career includes advancement from Assistant Professor to Associate Professor at CU Anschutz. He has earned prestigious awards, including the 2020 University of Washington School of Pharmacy “125 Legendary Alumni” Award, the 2010-2011 K-INBRE Faculty Recruitment Award, the 2009-2010 UCSF Postdoctoral Scholar Research Award, the 2005-2006 Merck Graduate Student Scholar Award, and the 2002-2005 NIH Pharmacological Sciences Training Grant Predoctoral Fellowship. He serves on the editorial boards of Nature Scientific Reports, Current Drug Metabolism, and PLOS One, and holds memberships in the American Chemical Society, International Society for the Study of Xenobiotics, American Society for Pharmacology and Experimental Therapeutics, Society of Toxicology, American Association of Colleges of Pharmacy, Sigma Xi Scientific Honor Society, and Biophysical Society. Key publications include "Role of protein–protein interactions in cytochrome P450-mediated drug metabolism and toxicity" (Kandel and Lampe, 2014), "Neonatal cytochrome P450 CYP3A7: A comprehensive review of its role in development, disease, and xenobiotic metabolism" (Li and Lampe, 2019), and "Two-dimensional NMR and all-atom molecular dynamics of cytochrome P450 CYP119 reveal hidden conformational substates" (Lampe et al., 2010). His work has amassed over 1,099 citations on Google Scholar, influencing advancements in pharmacokinetics and drug metabolism.