Always supportive and inspiring to all.
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Professor Jon Brown serves as Professor of Neurophysiology and Head of the Department of Clinical and Biomedical Sciences within the University of Exeter Medical School. He earned his PhD from the University of Bristol in 2004 and previously studied Neuroscience at the University of Manchester. As a neuroscientist, Brown specializes in neuronal and synaptic circuit dysfunction using rodent models of human neurological and psychiatric diseases. His research employs mainly electrophysiological techniques to investigate the neuronal basis of conditions such as Alzheimer's disease and dementia. Key areas include altered intrinsic neuronal excitability, epileptiform activity propagation, and EEG microstate complexity for early Alzheimer's diagnosis.
Brown's scholarly contributions are extensive, with over 4,150 citations on Google Scholar. Notable publications include 'EEG microstate complexity for aiding early diagnosis of Alzheimer’s disease' (2020), 'Altered intrinsic neuronal excitability and reduced Na+ currents in a mouse model of Alzheimer's disease' (2011), 'LPA1 receptor-deficient mice have phenotypic changes observed in psychiatric disease' (2003), 'Gabapentin is not a GABAB receptor agonist' (2001), 'Initiation and slow propagation of epileptiform activity from ventral to dorsal hippocampus in mouse models' (2018), and 'Pharmacological Characterisation of Nicotinic Acetylcholine Receptor-mediated Currents in Adult Mouse Cortical Interneurons' (2015). He led studies providing new insights into spatial disorientation in dementia as part of an Alzheimer's Research UK Senior Fellowship. Brown contributes to teaching, including modules on Introduction to Neuroscience in BSc Medical Sciences and BSc Neuroscience programs. He supervises PhD students and participates in funding initiatives such as the GW4 BioMed2 MRC Doctoral Training Partnership. As department head, he oversees academic leadership in clinical and biomedical sciences research and education.
