Rate My Professor Juan Perilla

Prof. Perilla's research specializes in molecular biophysics and the molecular mechanisms of HIV-1 infection, focusing on the structure, dynamics, and interactions of the HIV capsid with host factors. He has authored approximately 50 peer-reviewed articles, three book chapters, and 11 journal covers. Key publications include "Inositol phosphates are assembly co-factors for HIV-1" (Nature, 2018), "Dynamic regulation of HIV-1 capsid interaction with the restriction factor TRIM5α identified by magic-angle spinning NMR and molecular dynamics simulations" (PNAS, 2018), "Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics" (Nature, 2013), "Physical properties of the HIV-1 capsid from all-atom molecular dynamics simulations" (Nature Communications, 2017), and "Cyclophilin A stabilizes the HIV-1 capsid through a novel non-canonical binding site" (Nature Communications, 2016). His laboratory has performed the largest molecular dynamics simulations conducted to date and developed robust statistical analysis frameworks for massive datasets. With over 4,900 citations on Google Scholar, Prof. Perilla's work has significantly impacted computational structural biology. He was named a Mangone Young Scholar in 2023 and received the 2018 HPCwire Award for Best HPC Collaboration (Academia/Government/Industry), along with major supercomputing allocations such as 582,000 node hours on Blue Waters.