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Leslie L. Lovelace serves as Associate Chair, Director of Undergraduate Studies, and Professional Track Faculty in the Department of Chemistry and Biochemistry at the University of South Carolina. She obtained Bachelor of Science degrees in Biology in 1990 and Chemistry in 1994 from Francis Marion University. She further pursued advanced studies at the University of South Carolina, earning a Master of Science in Analytical Chemistry in 1997 and a Ph.D. in Biochemistry in 2005. Following her doctoral work, Lovelace completed a postdoctoral fellowship at the University of South Carolina. She joined the Department of Chemistry and Biochemistry as an instructor in January 2016, was appointed Director of Undergraduate Studies in 2017, and progressed to her current leadership roles, overseeing undergraduate programs and contributing to departmental administration.
Lovelace's scholarly contributions center on protein X-ray crystallography, structural chemistry, and enzyme mechanisms, with 27 publications garnering over 690 citations. Key works include 'Structures of K42N and K42Y sperm whale myoglobins point to an inhibitory role of distal water in peroxidase activity' (2014), 'Complexes of Dual Function Hemoglobin/Dehaloperoxidase with Substrate 2,4,6-Trichlorophenol Are Inhibitory and Indicate Halophenol Binding to Compound I' (2013), 'Structures of Asymmetric Complexes of Human Neuron Specific Enolase with Resolved Substrate and Product and an Analogous Complex with Two Inhibitors Indicate Subunits Interaction and Inhibitors Cooperativity' (2012), 'Mechanism of N¹⁰-formyltetrahydrofolate synthetase derived from complexes with intermediates and inhibitors' (2011), 'Structure of Human C8 Protein Provides Mechanistic Insight into Membrane Pore Formation by Complement' (2011), and 'Characterization and Inactivation of an Agmatine Deiminase from Helicobacter Pylori' (2010). Her excellence in teaching was recognized with the 2021 College of Arts and Sciences Undergraduate Teaching Award for Professional Faculty in sciences. Lovelace also serves on the Spring 2025 Inaugural Faculty Advisory Committee for the College of Arts and Sciences, aiding in faculty governance and elections. Through her roles, she profoundly influences undergraduate education and research training in chemistry.
