Rate My Professor Martial Say

Dr. Martial Venance Say is a professor of Chemistry at Georgia Gwinnett College. He earned his Ph.D. in chemistry from Georgia State University, where he was affiliated with the Department of Chemistry and contributed to numerous peer-reviewed publications in organic and medicinal chemistry. Following his doctoral work, Dr. Say served as a senior lecturer at the University of Félix Houphouët-Boigny in Abidjan, Ivory Coast, continuing his research in natural products and synthetic compounds.

Dr. Say's research specializations include the synthesis of DNA minor groove binders, antiparasitic agents, and other biologically active molecules. Key publications from his career encompass 'Practical Synthesis of 4-Chloro-2-(2-naphthyl)quinoline, a Precursor of Novel DNA Minor Groove Binders' (Organic Process Research & Development, 1998), 'Synthesis and Activity of Substituted 2-Phenylquinolin-4-amines against Plasmodium falciparum' (Journal of Medicinal Chemistry, 2003), and 'Triplex Selective 2-(2-Naphthyl)quinoline Compounds: Origins of Excited-State Proton Transfer from the Single Crystal X-Ray Structures' (Journal of the American Chemical Society, 2003). Additional significant works include 'Minor Groove Binding Compounds That Jump a GC Base Pair and Bind in the Minor Groove of DNA' (2013), 'Exploration of DAPI Analogues: Synthesis, Antitrypanosomal Activity, and DNA Binding of Novel Mono- and Bis-Amidine Derivatives' (Bioorganic & Medicinal Chemistry Letters, 2017), 'Synthesis of New Substituted 2-(Trimethylstannyl)indoles' (2008), 'Water-soluble pH-sensitive 2,6-bis(substituted ethylidene)cyclohexanones' (2004), and contributions to cassane diterpenoids isolation and synthesis of theophylline derivatives. These publications highlight his expertise in developing compounds for potential therapeutic use against parasites and DNA-targeted applications, influencing advancements in chemical biology and drug discovery.