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Mathew Byers is a Laboratory Technician in the Department of Medicine at the University of Otago, Christchurch, New Zealand, based at 2 Riccarton Avenue, Christchurch 8011. He holds an MSc and conducts research in biomedical science, with affiliations to the Christchurch Heart Institute, including participation in team events such as the City2Surf in 2017 with researchers like Vicky Cameron, Mark Appleby, and Adam Runesson. His contact direct dial is +64 3 364 3888.
Byers' research encompasses cryobiology and cardiovascular physiology. Early contributions include analyses of aldehydes in cryoprotectants for oocyte and embryo preservation. With Michael Legge, he published 'Varying amounts of different aldehydes present in the cryoprotectants dimethyl sulphoxide and 1,2-propanediol' in Reproduction, Fertility and Development in March 2012. He also co-authored conference papers: 'Identification and effect of aldehydes in oocyte and embryo cryoprotectants' in January 2001 and 'Should cryprotectants be formulated according to the mouse genome?' at the 13th International Mouse Genome Conference in December 1999. Transitioning to cardiac research, Byers co-authored 'Cardiac effects of myoregulin in ischemia-reperfusion' in Peptides (volume 174, April 2024, article 171156). The study, conducted using male Sprague-Dawley rats in an ex vivo Langendorff isolated heart model, reported myoregulin mRNA expression in human heart tissue but absence in plasma. Myoregulin, inhibiting sarco-endoplasmic reticulum Ca2+-ATPase (SERCA) to regulate calcium uptake, demonstrated cardio-protection by preserving left ventricular contractility and relaxation during ischemia/reperfusion. Collaborators included Sarah Appleby, Chris M. Frampton, Louise N. Paton, Richard Troughton, A. Mark Richards, and Christopher J. Pemberton. These works highlight Byers' technical expertise in experimental models for reproductive and heart research.

Photo by Osarugue Igbinoba on Unsplash
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