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Michele Krause is a Lab Technician in the Krause Group, Department of Biochemistry, School of Biomedical Sciences, within the Division of Health Sciences at the University of Otago. She provides critical technical support in cell and tissue culture maintenance, transfections, and HEK293 cell work, contributing to the department's research in structural biology, protein function, and infectious diseases. Her role is essential for experimental reproducibility and advancement of projects under Professor Kurt Krause.
Michele Krause's technical assistance is acknowledged in several peer-reviewed publications. In Couñago et al. (2015), 'Structures of Orf Virus Chemokine Binding Protein in Complex with Host Chemokines Reveal a Multimolecular Supermolecule with Broad Binding Specificity' published in Structure, she is thanked alongside Dr. Paula Jennings for cell culture assistance. This study details the crystal structures providing insights into viral immune evasion strategies. Similarly, Campbell et al. (2021), 'Optimisation of Neuraminidase Expression for Use in Drug Susceptibility Assays' in Viruses credits her for HEK cell maintenance and transfections, facilitating optimized expression systems for influenza neuraminidase in antiviral research. Kvach et al. (2019), 'Differential Inhibition of APOBEC3 DNA-Mutator Isozymes by Fluoro- and Non-Fluoro-Substituted 2'-Deoxyzebularine Embedded in Single-Stranded DNA' in ChemBioChem acknowledges her and Chisu Song for full-length APOBEC3G preparation, supporting investigations into inhibitors of these antiviral enzymes. Earlier, Couñago et al. (2010), 'Crystallization and preliminary X-ray analysis of the orf virus alkaline phosphatase' in Acta Crystallographica Section F thanks her for tissue culture maintenance. Department newsletters highlight her tissue culture expertise appreciated lab-wide. She has also provided photo credits for university news on TB research impacts (2021). Her consistent support enhances the Krause Group's productivity in biomedical research.
