Rate My Professor Paula Fischhaber

Fischhaber's research focuses on the molecular mechanisms of DNA repair pathways in Saccharomyces cerevisiae, particularly the temporal and spatial recruitment of end-processing factors such as Rad10, Saw1, and SLX4 during double-strand break repair, nucleotide excision repair, and single-strand annealing. As Principal Investigator, she has secured over $2.5 million in funding from the National Institutes of Health MBRS SCORE program, including SC1 GM127204 for 'SLX4 in Nuclease Recruitment' (2018-2024, $1,359,096), SC3 GM093858 for 'Recruitment of End-Processing Factors in DSB Repair' (2014-2018, $409,125), and earlier grants on Rad10 recruitment and protein relationships in nucleotide excision repair. Her peer-reviewed publications include 'Synthesis and Characterization of Amorphous Lawsone Polymer Dots for Fluorescent Applications' (ACS Applied Nano Materials, 2023), 'SAW1 is Increasingly Required to Recruit Rad10 as SSA Flap-Length Increases from 20-50 Base Pairs in Single-Strand Annealing in S. cerevisiae' (Biochemistry and Biophysics Reports, 2021), 'Saw1 Localizes to Repair Sites but is not Required for Recruitment of Rad10 to Repair Intermediates Bearing Short Non-Homologous 3′ Flaps during Single-Strand Annealing in S. cerevisiae' (Molecular and Cellular Biochemistry, 2016), and 'Rad51 ATP Binding but not Hydrolysis is Required to Recruit Rad10 in Synthesis-Dependent Strand Annealing in S. cerevisiae' (Advances in Biological Chemistry, 2013). She has also contributed to intradepartmental grants and infrastructure development, such as the CSUPERB-funded Instructional Tissue Culture Facility (2007-2008).