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About Quentin
Professor Quentin M. Anstee is Pro-Vice-Chancellor of the Faculty of Medical Sciences at Newcastle University, where he holds the Ruth and Lionel Jacobson Chair in Personalised Medicine. He serves as Professor of Experimental Hepatology and is an Honorary Consultant Hepatologist in the Liver Unit at Freeman Hospital, Newcastle upon Tyne. Anstee trained in medicine at University College London, earning a BSc (Hons) 1st Class in Cell Pathology and Basic Medical Sciences in 1994 and an MB BS with Distinction in Medicine in 1997, receiving the First Prize in Medicine (The Philip Seth Belasco & Douglas Cree Prize). He obtained his PhD from Imperial College London in 2007, is a Member of the Royal College of Physicians (MRCP(UK), 2000), and a Fellow of the Royal College of Physicians (FRCP, 2016). Prior to joining Newcastle University in 2010, he worked as Clinical Lecturer in Medicine and Hepatology at Imperial College London and St Mary’s Hospital from 2007 to 2010. He previously served as Dean of Research & Innovation.
Anstee’s translational research centres on the pathophysiology, natural history, diagnosis, and treatment of metabolic dysfunction-associated steatotic liver disease (MASLD), formerly non-alcoholic fatty liver disease (NAFLD), and its progression to steatohepatitis, cirrhosis, and hepatocellular carcinoma. He has coordinated major international consortia including EPoS (Elucidating Pathways of Steatohepatitis, EU H2020 €6 million, 2015-2019) and LITMUS (Liver Investigation: Testing Marker Utility in Steatohepatitis, EU IMI2 €47.3 million, 2017-2024), leads the European MASLD Registry, and is chief investigator of clinical trials for new MASLD therapies such as those evaluating ervogastat and semaglutide. His work has advanced understanding of genetic and epigenetic modifiers of disease progression and biomarker development for diagnosis and risk-stratification. An NIHR Senior Investigator and Web of Science Highly Cited Researcher in the top 1% by citations, he is an Associate Editor of the Journal of Hepatology and a Fellow of the Association of Physicians of Great Britain and Ireland. He established the regional MASLD specialist clinical service and manages complex liver conditions including alcoholic liver disease, viral hepatitis, autoimmune liver diseases, cirrhosis, and liver transplantation.
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