Rate My Professor Ranjita Betarbet

Ranjita Betarbet, PhD, serves as Assistant Professor in the Department of Neurology at Emory University School of Medicine. She holds the position of Senior Scientific Administrator at the Center for Neurodegenerative Disease and is an adjunct member of the Neuroscience Graduate Program. Betarbet obtained her PhD from the All India Institute of Medical Sciences in New Delhi and her MS from the University of Delhi. Her academic career at Emory encompasses research administration, training grant oversight, and contributions to Alzheimer's disease research initiatives, including pilot projects and research education components.

Betarbet's research centers on the pathogenesis and pathology of neurodegenerative diseases, with a focus on interactions between Parkinson’s and Alzheimer’s disease-related genetic factors and external stressors, including mitochondrial impairment, oxidative stress, protein degradation, and protein trafficking pathways, and their roles in neurodegeneration. She has authored numerous publications in high-impact journals. Notable works include 'Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level' (Nature Neuroscience, 2022), 'Cell type-specific biotin labeling in vivo resolves regional neuronal and astrocyte proteomic differences in mouse brain' (Nature Communications, 2022), and 'Open drug discovery in Alzheimer’s disease' (Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2023). Recent contributions feature 'Integrated phenotypic and proteomic screening identifies top-tier Alzheimer’s disease therapeutic targets' and 'PAK1 inhibitor NVS-PAK1-1 preserves dendritic spines in amyloid/tau exposed neurons and 5xFAD mice' (Alzheimer's & Dementia, 2025). Earlier influential papers include 'An In Vitro Model of Parkinson’s Disease' (Journal of Neuroscience, 2002). Her work advances understanding of proteomic changes and potential therapeutic targets in neurodegenerative disorders.