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Rate My Professor Sara Crellin

University of Otago

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5.04/23/2026

Makes learning engaging and enjoyable.

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About Sara

Sara Crellin is a researcher affiliated with the Department of Psychological Medicine in the Dunedin School of Medicine, Faculty of Medicine, University of Otago. She completed her Doctor of Philosophy degree in 2025 with a thesis titled 'Mode of action of bipolar disorder therapeutics, novel ex vivo screening methods and EEG dynamics in humans.' Supervised by Professor Paul Glue, Professor Dirk De Ridder, Associate Professor Phil Sheard, and Dr Phil Heyward, her doctoral research investigated the underlying mechanisms of bipolar disorder treatments. Crellin focused on how therapeutics such as lithium influence the flow of electricity along neural connections, specifically axonal conduction in brain regions associated with emotion and cognition. She developed a novel ex vivo mouse lateral olfactory tract preparation to enable pharmacological and electrophysiological studies of axonal function, addressing a gap in prior research that had not examined these aspects despite clinical neuroimaging evidence of compromised axonal integrity in bipolar disorder. Her work explores neural network dynamics and potential new therapeutic targets, aiming to improve treatments, diagnostics, and public understanding of bipolar disorder as a physiological condition affecting cellular function in the brain.

Rate My Professor Sara Crellin | University of Otago