Helps students see the bigger picture.
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Sonia Nielles-Vallespin is an Associate Professor in Cardiac Magnetic Resonance Physics at the National Heart and Lung Institute, Faculty of Medicine, Imperial College London, and serves as Head of Cardiovascular Magnetic Resonance Physics at the Royal Brompton Hospital. She obtained her PhD in Magnetic Resonance Imaging from Heidelberg University in 2004, following earlier degrees including an MSc and BSc from the University of Aberdeen. Prior to her current roles, she held a position at the National Heart, Lung, and Blood Institute of the National Institutes of Health.
Her academic interests center on medical imaging and MRI techniques, with a specialization in diffusion tensor cardiovascular magnetic resonance for assessing myocardial microstructure. Nielles-Vallespin's research has advanced in vivo imaging methods to detect microstructural changes in the heart, such as laminar disarray in hypertrophic cardiomyopathy and dynamic alterations following acute myocardial infarction. She has contributed to optimizing perfusion CMR sequences and developing spiral phyllotaxis trajectories for 3D radial MRI sampling. With over 4,200 citations on Google Scholar, her influence is evident in highly cited works including 'Assessment of Myocardial Microstructural Dynamics by In Vivo Diffusion Tensor Cardiac Magnetic Resonance' (Journal of the American College of Cardiology, 2017, 314 citations), 'Myocardial Perfusion Cardiovascular Magnetic Resonance: Optimized Dual Sequence and Reconstruction for Quantification' (2016, 406 citations), 'Spiral Phyllotaxis: The Natural Way to Construct a 3D Radial Trajectory in MRI' (Magnetic Resonance in Medicine, 2011, 292 citations), 'In vivo cardiovascular magnetic resonance diffusion tensor imaging shows evidence of abnormal myocardial laminar orientations and mobility in hypertrophic cardiomyopathy' (2014, 270 citations), and 'In vivo diffusion tensor MRI of the human heart: reproducibility of breath-hold and navigator-based approaches' (2013, 245 citations). Recent efforts include deep learning acceleration for cardiac DTI and field strength effects on diffusion measurements. She leads a team pioneering advanced CMR physics for non-invasive myocardial evaluation and has secured funding for novel high-field heart scanners. Nielles-Vallespin engages in the scientific community through involvement in the Cardiac Diffusion Special Interest Group of the Society for Cardiovascular Magnetic Resonance and delivers invited seminars on cardiac microstructure.
