Rate My Professor Steven Petratos

Petratos specializes as a neurobiologist in defining the molecular mechanisms that govern neurodegeneration in multiple sclerosis, with research keywords encompassing stem cell therapies, multiple sclerosis, Alzheimer's disease, brain disorders, and drug development. His ongoing projects include the preclinical development of the thyroid hormone analogue DITPA to enhance brain repair during MS-like disease by protecting cells and promoting nerve fiber repair; utilizing genetically modified haematopoietic stem cells as a therapeutic delivery system to minimize and reverse MS progression; and developing small molecules to promote remyelination in multiple sclerosis. He supervises PhD students on projects such as overcoming MCT8-dependent oligodendrocyte dystrophy for neuroprotection and neurorepair. Key publications include "Nogo receptor-Fc delivered by haematopoietic cells enhances neurorepair in a multiple sclerosis model" (Brain Communications, 2023), "The iron maiden: Oligodendroglial metabolic dysfunction in multiple sclerosis and mitochondrial signaling" (Neuroscience and Biobehavioral Reviews, 2024), "How does Nogo-A signalling influence mitochondrial function during multiple sclerosis pathogenesis?" (Neuroscience and Biobehavioral Reviews, 2024), "How does Nogo receptor influence demyelination and remyelination in the context of multiple sclerosis?" (Frontiers in Cellular Neuroscience, 2023), "Limiting neuronal Nogo receptor 1 signaling during experimental autoimmune encephalomyelitis (EAE) preserves axonal transport and abrogates inflammatory demyelination" (Journal of Neuroscience, 2019), and "Overcoming monocarboxylate transporter 8 (MCT8)-deficiency to promote human oligodendrocyte differentiation and myelination" (EBioMedicine, 2017). His research contributes to Sustainable Development Goal 3: Good Health and Well-being.