Rate My Professor Timothy Tree

Tree specializes in human T cell immunology, with particular expertise in the function of regulatory T cells in human health, disease, and transplantation. His research explores autoreactive T cells and develops strategies to strengthen immune regulation, notably in type 1 diabetes and amyotrophic lateral sclerosis. Current projects include identifying cerebrospinal fluid and blood immune biomarkers for ALS progression and IL-2 therapy response, cooperative harmonization of islet-specific antigen-induced memory T cell assays, and precision profiling of proinsulin-specific CD4 T cells in relation to pathogenic autoimmunity and viral infection. He received the RD Lawrence Fellowship from Diabetes UK in 2001. His scholarly impact is evidenced by over 7,220 citations. Key publications include 'Defective suppressor function in CD4+CD25+ T-cells from patients with type 1 diabetes' (Diabetes, 2005; 1,220 citations), 'Guidelines for the use of flow cytometry and cell sorting in immunological studies' (European Journal of Immunology, 2019; 2,386 citations), 'Regulatory T cell dysfunction in type 1 diabetes: what’s broken and how can we fix it?' (Diabetologia, 2017; 274 citations), 'Safety and immunogenicity of one versus two doses of the COVID-19 vaccine BNT162b2 for patients with cancer' (The Lancet Oncology, 2021; 678 citations), and 'Efficacy and safety of low-dose IL-2 as an add-on therapy to riluzole (MIROCALS)' (The Lancet, 2025).