Rate My Professor Wenji Dong

Dr. Dong's research interests center on understanding Ca²⁺-activated regulation of cardiac myofilament in healthy and diseased hearts using fluorescence spectroscopic approaches including FRET, designing and developing microfluidic sensors for biological, cellular research, and clinical applications in early diagnosis of diseases, and developing novel luminescent materials and approaches for solar energy harvest such as wavelength-shifting materials and solar concentrators. Key publications include "Role of the C-terminus mobile domain of cardiac troponin I in the regulation of thin filament activation in skinned papillary muscle strips" (2018), "Functional significance of C-terminal mobile domain of cardiac troponin I" (2017), "Dynamic Equilibrium of Cardiac Troponin C’s Hydrophobic Cleft and Its Modulation by Ca²⁺ Sensitizers and a Ca²⁺ Sensitivity Blunting Phosphomimic, cTnT(T204E)" (2017), "Fluorescence based characterization of calcium sensitizer action on the troponin complex" (2016), "Increased titin compliance reduced length-dependent contraction and slowed cross-bridge kinetics in skinned myocardial strips from Rbm20ΔRRM mice" (2016), and "In situ time-resolved FRET reveals effects of sarcomere length on cardiac thin-filament activation" (2014). His recognition includes the Paul Hohenschuh Distinguished Professorship.