"Assistant Professor, Clemson Center for Human Genetics - Greenwood SC"

Assistant Professor, Clemson Center for Human Genetics - Greenwood SC

Clemson University: College of Science: Genetics & Biochemistry

Location: Greenwood Genetics Center
Open Date: Sep 11, 2025

Description
Clemson University invites applications for two tenure track Assistant Professors at the Center for Human Genetics, with an expected start date of August 2026. The positions are in the general areas of computational/statistical genetics and molecular genetics/functional genomics. Clemson University offers competitive salaries, benefits, and start-up funds.

The successful applicant for the first position will have an accomplished research record at the forefront of human computational/statistical genetics and genomics. Areas of interest include, but are not limited to, quantitative genetics, statistical genetics, systems genetics of complex traits and inference of gene regulatory networks from single cell sequencing, using explainable artificial intelligence and machine learning models that incorporate multiomic data and environmental exposures to improve disease and quantitative trait prediction. Strong candidates will be able to develop, evaluate, prototype, and ultimately implement cutting edge statistical, computational, and machine learning/artificial intelligence methods for the integrative analysis of large-scale genetic and genomic data. However, all computational research areas with the potential to significantly advance the field of human genetics will be considered.

The successful applicant for the second position will have an accomplished research record at the forefront of human genetics and genomics. Areas of interest include, but are not limited to: cell culture and CRISPR gene editing in cell lines, differentiated induced pluripotent stem cells and organoids to functionally validate polymorphisms and their mechanism of action associated with human quantitative traits and disease; epigenetic analysis to infer the mechanism(s) by which variants in non-coding DNA are associated with disease and quantitative traits; and utilizing gene expression, chromatin conformation and spatial location at the single cell level to construct multilocus tissue-specific gene regulatory networks associated with diseases and quantitative traits.

The successful applicant will be part of a collaborative and interdisciplinary environment that includes the research, diagnostic and clinical geneticists at the Greenwood Genetic Center, the genetics, genomics, statistics and bioinformatics faculty at Clemson University, the USC School of Medicine in Greenville and the Prisma Health System.

About the Center for Human Genetics
The mission of the Center for Human Genetics is to understand the principles and mechanisms by which genetic and environmental factors affect human health and disease. The Center for Human Genetics provides a vibrant interactive research environment with state-of-the-art genomic and computational resources. The Center for Human Genetics has received a ~$10 million Phase 1 National Institutes of Health (NIH) Center of Biomedical Research Excellence in Human Genetics grant to mentor young faculty to obtain substantial NIH support for their research programs. The Center of Human Genetics currently consists of 31 faculty and their laboratory groups in nine Departments or Schools in four Colleges, located on the Clemson main campus and in Greenwood, South Carolina on the Greenwood Genetic Center Partnership Campus. Research facilities for the successful candidate will be in Self Regional Hall, a 17,000-square-foot building located in Greenwood, South Carolina on the Greenwood Genetic Center Partnership Campus.

The tenure home departments/schools are open. These include the School of Mathematical and Statistical Sciences, the School of Computing, the Department of Genetics and Biochemistry and the Department of Biological Sciences.

For more information about the Center for Human Genetics and its programs, please visit the website: https://scienceweb.clemson.edu/chg/

Qualifications
Successful candidates must hold a doctoral degree and have postdoctoral experience. Competitive candidates will demonstrate an ability to develop a vigorous and independent, externally funded and nationally recognized research program; demonstrate teaching excellence and a commitment to diversity inclusion; and participate in relevant undergraduate and graduate education programs.

Application Instructions
Review of applications will begin immediately; however, the position will remain open until filled.

Applicants should submit the following items via Interfolio at: https://apply.interfolio.com/173761

(1) Cover letter

(2) Curriculum Vitae

(3) Statement of research interests including future plans

(4) Statement of teaching interests and experience

(5) Up to three reprints in on PDF

(6) Three confidential letters of recommendation

Inquiries should be directed to Dr. Trudy Mackay (tmackay@clemson.edu).