"Clinical Research Project Manager A/B/C"

Job Description Summary

Manages day-to-day operations of clinical research projects under guidance from senior staff. Assists with protocol development, project coordination at single or multicenter sites, and quality control of data. Supports grant applications, prepares reports and presentations, and contributes to dissemination of study findings. May supervise project staff and participate in study visits.

Clinical Research Project Manager A:

Responsibilities include assisting with study start-up and maintenance activities, such as preparing and organizing study documents (protocols, informed consent forms, CRFs), supporting IRB submissions and amendments, tracking regulatory approvals, maintaining study binders, and assisting with development and upkeep of the study's Manual of Procedures (MOP). The Project Manager A supports preparation of meeting materials, reports, and study communications.

This role coordinates study activities across internal teams and external collaborators, assists with scheduling meetings, tracking timelines and milestones, and supporting communication among investigators, study staff, and partners. The Project Manager A also assists with quality control efforts by tracking staff training and certifications, supporting monitoring activities, and ensuring adherence to established study procedures and regulatory requirements.

The Project Manager A works closely with the PI, Clinical Research Coordinators, and grants management staff to support operational needs, including basic budget tracking and documentation. Serves as a point of contact for routine study-related inquiries and escalates complex issues as needed. Requires strong organizational skills, attention to detail, and effective communication. Works with moderate supervision and increasing independence over time. Serves as a primary liaison between the PI and study stakeholders, including Steering Committees, investigators, study staff, consultants, the IRB, and NIH. Works with the PI and grants management to oversee study budgets. Other duties as assigned.

Clinical Research Project Manager B:

Responsibilities include leading study start-up activities, such as developing study documents (protocols, informed consent forms, CRFs), obtaining single IRB approval, preparing meeting materials and presentations, and designing, maintaining, and enforcing the study's Manual of Procedures. The Project Manager B manages quality assurance and quality control activities, including staff training, data monitoring, certification tracking, and ensuring adherence to study and regulatory requirements.

The Project Manager B collaborates with internal teams and external partners nationwide, overseeing study operations, timelines, and deliverables. In addition, the Project Manager B supports junior faculty research efforts, assists with grant development and submissions, and may lead subprojects or provide supervisory support as needed. Requires minimal supervision, strong communication skills, and demonstrated expertise in clinical research operations. Other duties as assigned.

Clinical Research Project Manager C

Will serves as the primary liaison to internal teams, external collaborators, federal agencies, and funding sponsors. This role supervises and mentors project staff, while standardizing training, quality assurance, and operational practices across the program. Actively supports junior investigators in developing and executing research projects. include leading preparation and submission of large-scale grants (including multi-PI and center-level applications), managing budgets across active studies in collaboration with grants management, and overseeing dissemination efforts such as manuscripts and abstracts. This role requires a high degree of independence, advanced leadership skills, and extensive expertise in clinical research operations. Other duties as assigned.

Qualifications

Clinical Research Project Manager A:

Bachelor's Degree and 3-5 years of clinical research experience - The Research Project Manager A supports NIHfunded, investigator-initiated clinical research studies under the guidance of the PI. This role is intended for individuals developing project management and regulatory expertise. The candidate should have experience assisting with study start-up and maintenance activities, including preparation of study documents (protocols, consent forms, CRFs, SOPs) and supporting IRB submissions and amendments. Familiarity with human subjects protection regulations is preferred. Strong organizational, communication, and writing skills are required, along with the ability to manage multiple tasks, meet deadlines, and work effectively both independently and as part of a team. The role is performed with moderate supervision and offers opportunities for continued training and growth. Supervisory responsibilities are not typical but may include limited task guidance.

Clinical Research Project Manager B:

Master's Degree and 3-5 years of clinical research experience - Experience in clinical research and managing epidemiologic studies is preferred, along with previous experience drafting protocols, consent forms, and related SOPs. Strong problem-solving, communication, and writing skills are required, as well as the ability to manage multiple priorities and tasks. The candidate must be capable of working both independently and as part of a team, with effective time management and mature judgment. Knowledge of IRB and human research protection regulations is essential. Will provide supervisory duties, as necessary.

Clinical Research Project Manager C:

Master's Degree and 5+ years of clinical research experience - Extensive experience is required, including the independent management of complex, multi-site studies. The ideal candidate will have a strong track record of leading research operations, developing regulatory documents, and ensuring compliance. Demonstrated expertise in coordinating multi-disciplinary teams. Strong leadership, critical thinking, and communication skills are required, as well as the ability to prioritize and manage competing deadlines across multiple projects. The candidate must work well independently with minimal oversight, exercise sound judgment, and bring strategic insight to program development and study design. Familiarity with IRB processes and human subjects protection regulations is essential. This is a senior-level position with program-wide impact, including responsibilities for staff mentorship, cross-study coordination, and high-level problem-solving.

The position is contingent upon grant funding.

Job Location - City, State

Philadelphia, Pennsylvania

Department / School

Perelman School of Medicine

Pay Range

$62,000.00 - $106,940.00 Annual Rate

Salary offers are made based on the candidate's qualifications, experience, skills, and education as they directly relate to the requirements of the position, and in alignment with salary ranges based on external market data for the job's level. Internal organization and peer data at Penn are also considered.

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