"Laboratory Sciences Professional (Open Rank)"

Laboratory Sciences Professional (Open Rank)

University of Colorado Anschutz

Department: Pediatrics, Section of Developmental Biology

Official Title: Laboratory Sciences Professional (Open Rank)

Position #: 00811014 - Requisition #: 39231

Job Summary:

The Zhu Laboratory at the University of Colorado Anschutz Medical Campus is seeking a highly motivated Research Services Professional to join a dynamic team focused on stem cell biology, regenerative medicine, and diabetes research. Our lab investigates how human pluripotent stem cells differentiate into pancreatic β-cells and applies cutting-edge tools-including CRISPR-based engineering, genomics, artificial intelligence-guided regulatory design, and functional metabolic assays-to develop next-generation cell therapies for type 1 diabetes.

This position offers the opportunity to contribute directly to high-impact translational research. The selected candidate will perform molecular and cellular experiments, support stem cell differentiation workflows, and assist in developing and optimizing functional assays that evaluate β-cell identity and performance. At the senior level, this role includes independent experimental planning, assay development, and active participation in data interpretation and research advancement.

Key Responsibilities:

• Perform basic molecular biology techniques, including buffer preparation, sample collection, RNA/DNA extraction, PCR, real-time qPCR, cloning, bacterial culture, mini-prep, sequencing, sample submission, gel electrophoresis, Western blotting, immunofluorescence staining, and fluorescence microscopy.
• Maintain laboratory organization, including receiving and logging reagents/products, tracking inventory, autoclaving materials, managing biological waste, and general laboratory upkeep.
• At the Senior level, perform mammalian cell culture, static and dynamic glucose-stimulated insulin secretion assays, luciferase/reporter assays, lentiviral production and transduction, and flow cytometry analysis after training.
• Accurately document experiments, organize data, and communicate results to the PI and lab team.
• Assist with laboratory protocols, SOP updates, and ordering supplies.
• Comply with all institutional guidelines for biosafety, chemical safety, and research integrity.

Work Location:

Onsite - this role is expected to work onsite and is located in Aurora, CO.

Why Join Us:

Are you passionate about cutting-edge science and motivated to make a real-world impact on human health? Join the Zhu Lab at the University of Colorado Anschutz Medical Campus, where we are pushing the boundaries of stem cell biology and regenerative medicine to develop transformative therapies for type 1 diabetes.

Our team investigates how human pluripotent stem cells become pancreatic β-cells and engineers next-generation stem cell-derived islets with improved precision, stability, and therapeutic potential. We integrate molecular biology, genomics, CRISPR-based genome engineering, artificial intelligence-guided regulatory design, and functional metabolic assays to answer fundamental questions in development while accelerating translation toward clinical application. As part of our team, you will gain hands-on experience with advanced technologies in a high-impact, fast-paced research environment. You will contribute directly to projects aimed at improving β-cell specification and developing innovative strategies for diabetes therapy. This role offers meaningful opportunities for technical growth, scientific development, and active participation in research with direct translational relevance.

The University of Colorado Anschutz Medical Campus provides a vibrant, interdisciplinary scientific community with state-of-the-art research facilities and strong collaborations across basic science and clinical departments.

Qualifications:

Minimum Qualifications:

Intermediate Level:

• Bachelor's degree in biology, molecular biology, cell biology, biochemistry, genetics, bioengineering, or a related field.
• One (1) year of experience in an experimental or wet laboratory.

Senior Level:

• Bachelor's degree in biology, molecular biology, cell biology, biochemistry, genetics, bioengineering, or a related field.
• Two (2) years of experience in an experimental or wet laboratory.

Substitution (All Levels): A combination of education and related technical/military/paraprofessional experience may be substituted for a bachelor's degree on a year-for-year basis.

Applicants must meet minimum qualifications at the time of hire.

Applicants must be legally authorized to work in the United States without requiring sponsorship. We are unable to provide work visa sponsorship or employment authorization for this position now or in the future.

Preferred Qualifications (All Levels):

• Experience with mammalian cell culture, including maintenance, passaging, and basic functional assays.
• Hands-on experience with CRISPR-based workflows, such as plasmid preparation, cloning, or genotyping validation.
• Experience performing flow cytometry sample preparation, acquisition, or analysis.
• At least one (1) year of full-time laboratory research experience in molecular biology, stem cell biology, developmental biology, or a related field beyond coursework.

Conditions of Employment (All Levels):

• Must be willing and able to pass a national criminal background check.

Knowledge, Skills, and Abilities:

Intermediate Level:

• Ability to follow established laboratory protocols with accuracy and attention to detail.
• Ability to learn new laboratory techniques and incorporate feedback into daily work.
• Ability to maintain clear, organized experimental records and document results consistently.
• Ability to manage time effectively and complete assigned tasks with minimal supervision.
• Ability to work cooperatively within a research team and contribute to shared responsibilities.

Senior Level:

• Ability to independently plan, execute, and troubleshoot laboratory procedures.
• Ability to adapt to evolving project needs and implement new technical approaches.
• Ability to organize, prioritize, and coordinate multiple experiments simultaneously.
• Ability to document and interpret experimental results with a high level of accuracy.
• Ability to assist in guiding junior lab members and support a collaborative research environment.

How to Apply:

For full consideration, please submit the following document(s):

1. A letter of interest describing relevant job experiences as they relate to the listed job qualifications and interest in the position
2. Curriculum vitae / Resume
3. Three to five professional references, including name, address, phone number (mobile number if appropriate), and email address

Questions should be directed to: Han Zhu

Screening of Applications Begins:

Immediately and continues until the position is filled. For best consideration, apply by April 6, 2026.

Anticipated Pay Range:

• Intermediate Level: $50,357 to $64,054
• Senior Level: $54,440 to $69,248