PhD Candidate in Genomic Instability in Cancer

Location: Edmond J. Safra Campus, Givat Ram, Jerusalem, Israel

About Our Campus: Hebrew University’s Edmond J. Safra Campus is a vibrant hub of academic and research excellence nestled in the heart of Jerusalem. Our modern campus boasts state-of-the-art lab facilities, world-renowned faculty, and a stimulating environment that fosters scientific exploration, intellectual growth, and innovation.

About Our Department: The Genetics Department at the Alexander Silberman Institute of Life Science at the Hebrew University. Our Department encourages a broad approach to genetics and epigenetics, studying how genes, chromosomes, and genomes are inherited, packaged, and regulated. We explore genome protection, gene expression, RNA regulation, and human evolution, using a variety of model organisms and cell types. Our diverse yet collaborative research fosters a vibrant scientific community.

About Our Research: The Batsheva Kerem Laboratory at the Life Sciences Institute studies the molecular biology of cancer, focusing on genomic instability during early cancer development. Our research investigates the impact of oncogenes and tumor suppressors on DNA replication dynamics, replication timing, transcription, and chromatin remodeling. Our goal is to understand how perturbations in cancer-related pathways lead to specific breakpoint signatures. We aim to uncover fundamental mechanisms of cancer development with the support of a recently awarded NIH grant.

Job Description: We are looking for exceptionally qualified PhD candidates to join our lab at the Batsheva Kerem Laboratory. The selected candidate will be involved in innovative research exploring genomic instability and its role in cancer development. This position provides an opportunity to work in an interdisciplinary environment, employing advanced techniques to understand the molecular processes underlying early cancer progression.

About Your Supervisor: Prof. Batsheva Kerem is a full professor at the Department of Genetics, Life Sciences Institute at the Hebrew University. She completed her B.Sc. and Ph.D. at the Hebrew University and conducted postdoctoral research at the Hospital for Sick Children in Toronto, where she helped identify the CFTR gene linked to Cystic Fibrosis. Her research focuses on cancer genomic instability and personalized medicine for Cystic Fibrosis, aiming to uncover the mechanisms behind genome instability in cancer and develop new therapies for Cystic Fibrosis patients.

Funding: 2200 USD monthly.

Your Profile (To excel in this role, we seek candidates with):

• A background in molecular and cell biology.
• Additional experience in bioinformatics is advantageous.
• High motivation and excellent communication skills.

Application: Please submit the following documentation as three separate PDF files:

• Letter of motivation
• CV (including a list of publications)
• Copy of your original academic degree(s)

Application Deadline: 2026-03-16 23:59 (Asia/Jerusalem)

Job type: PhD

Field: Bioinformatics, Molecular Biology, Cell Biology, Cancer Research