"Post-Doc Research Associate_Hahn Lab"

Department: Pharmacology - 424001

Posting Open Date: 03/24/2022

Open Until Filled: Yes

Position Type: Postdoctoral Scholar

Position Title: Post-Doc Research Associate_Hahn Lab

Vacancy ID: PDS003418

Full-time/Part-time: Full-Time Temporary

Hours per week: 40

FTE: 1

Work Location: Chapel Hill, NC

Position Location: North Carolina, US

Estimated Duration of Appointment: 12 Months

Primary Purpose of Organizational Unit: The UNC School of Medicine has a rich tradition of excellence and care. Our mission is to improve the health and wellbeing of North Carolinians, and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education, and research. We strive to promote faculty, staff, and learner development in a diverse, respectful environment where our colleagues demonstrate professionalism, enhance learning, and create personal and professional sustainability. We optimize our partnership with the UNC Health System through close collaboration and commitment to service. Our vision is to be the nation’s leading public school of medicine. We are ranked 2nd in primary care education among all US schools of medicine and 5th among public peers in NIH research funding. Our Allied Health Department is home to five top-ranked divisions, and we are home to 18 top-ranked clinical and basic science departments in NIH research funding. Our mission is to improve the health and well-being of North Carolinians and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education, and research. Patient Care: We will promote health and provide superb clinical care while maintaining our strong tradition of reaching underserved populations and reducing health disparities across North Carolina and beyond. Education: We will prepare tomorrow’s health care professionals and biomedical researchers by facilitating learning within innovative curricula and team-oriented interprofessional education. We will cultivate outstanding teaching and research faculty, and we will recruit outstanding students and trainees from highly diverse backgrounds to create a socially responsible, highly skilled workforce. Research: We will develop and support a rich array of outstanding health sciences research programs, centers, and resources. We will provide infrastructure and opportunities for collaboration among disciplines throughout and beyond our University to support outstanding research. We will foster programs in the areas of basic, translational, mechanistic, and population research.

Position Summary: Postdocs in organic and physical organic chemistry, to study and develop novel environment-sensing dyes and protein-dye conjugates, including structures for single molecule imaging in vivo, and for multiplexed biosensor/optogenetic imaging (J. Am. Chem. Soc. 141(18): 7275, 2019. PMC6572722). Projects here will focus on the GTPase cycle and on exocysts. We offer an opportunity for chemists to learn protein engineering and microscopy, and to apply their own new probes to answer cell biology questions. This project involves novel approaches for specific derivatization of proteins within live cells.

Minimum Education and Experience Requirements: Doctorate in pharmacology, chemistry or related field.

Required Qualifications, Competencies, and Experience: Experience with developing novel environment-sensing dyes and protein-dye conjugates, including structures for single molecule imaging in vivo, and for multiplexed biosensor/optogenetic imaging.

Preferred Qualifications, Competencies, and Experience: Experience with GTPase cycle and on exocysts. Protein engineering and microscope experience.

Special Instructions: For information on UNC Postdoctoral Benefits and Services click here