"Post-Doctoral Fellow - Pietras Laboratory"

Job Summary

This position reports directly to Dr. Eric Pietras, PhD, and will work within the Pietras Lab, a component of the School of Medicine's Hematology Division.

This position is involved in studies aimed at defining the biology of acute myeloid leukemia stem cells. Specifically, the Fellow will help investigate the role of metabolism in the biology and pathogenesis of acute myelogenous leukemia. The Fellow is expected to conduct research projects, to think independently, be highly motivated, design and carry out experiments, analyze data, and interpret and publish results. It is the Fellow's responsibility to fully understand the technical details of Dr. Pietras' projects as well as how each applies within the larger context of defining novel therapeutic agents in Hematological Research.

Key Responsibilities

This position is expected to work independently under the guidance of the principal investigator. Projects will involve work with research animals and extensive development and use of cutting-edge flow cytometry, molecular biology and cell biology assays on rare bone marrow-derived hematopoietic populations. Specific duties include:

Design and Performance of Research Experiments (75% of Time Spent)

• Mechanism based discovery of cancer therapeutics.
• Characterization of metabolic processes of leukemia stem cells.
• Use of animal model systems to study leukemia pathogenesis.

Analysis and Publication of Research Data (20% of Time Spent)

• Prepare data and manuscripts for publication
• Prepare grant proposals to obtain independent post-doctoral funding
• Actively participate in and present data at group meetings, journal clubs and conferences
• Work in conjunction with the PI and other lab staff to achieve programmatic goals, including student supervision

Mentoring of students and technical staff (5% of Time Spent)

Other duties as assigned

To fulfill job requirements, candidates must receive training and adhere to institutional standards of best practice in: animal care and handling, radiation and chemical safety, laboratory safety and other areas as determined by the institution and/or PI.

This description is a summary only and describes the general level of work being performed, it is not intended to be all-inclusive. The duties of this position may change from time to time and/or based on business need. We reserve the right to add or delete duties and responsibilities at the discretion of the supervisor and/or hiring authority.

Work Location

Onsite - this role is expected to work onsite and is located on the Anschutz Medical Campus in Aurora, Colorado.

Why Join Us

The Department of Medicine, Hematology/Oncology/Bone Marrow Transplant Laboratories, at the University of Colorado Anschutz Medical Campus (CU-AMC), is looking for a bright, creative and enthusiastic Post-Doctoral Fellow interested in advancing their career in a high-impact laboratory headed by an energetic, principal investigator, Dr. Eric Pietras, PhD. The lab is part of a richly collaborative interdisciplinary group of basic scientists and clinicians from immunology, hematology and molecular biology backgrounds with significant resources.

Qualifications

Minimum Qualifications

• A doctoral level degree (PhD, MD, MD/PhD) in immunology, stem cell biology, experimental hematology, molecular biology, or equivalent from an accredited institution.
• At least one first-author publication in an internationally recognized, peer-reviewed journal.

Conditions of Employment:

• Candidate must be able to work with laboratory animals and animal tissues.
• Candidate must meet eligibility requirements for NIH T32 and F32 postdoctoral fellowship awards.

Preferred Qualifications

• Graduate training in a biomedical laboratory setting, studying immunology, molecular biology, hematology and/or stem cell biology.
• Experience with the use of advanced flow cytometry equipment (including LSRII and FACSAria II) for analysis and sorting of cells, and development of multicolor antibody staining panels.
• Experience in mouse handling, husbandry and dissection.
• Experience in experimental hematology and molecular biology assays and techniques, including HSC isolation and analysis, and high-throughput sequencing.
• Candidates that have successfully obtained competitive, extramural funding during their doctoral studies are preferred.

Knowledge, Skills and Abilities

• Excellent written and verbal communication skills in English.
• Ability to work independently and as a team member within a research environment.
• Ability to work efficiently and effectively with computer software including Microsoft Office.
• Skilled with the use of aseptic mammalian cell culture techniques.
• Skilled with common laboratory techniques and equipment consistent with PhD-level graduate training.
• Ability to commit to an independent scientific career in stem cell biology, immunology, or a related field, with a proven high degree of independence and self-motivation to achieve these ends.
• Ability to work a flexible schedule based on the needs of the project.

How to Apply

For full consideration, please submit the following document(s):

1. A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position
2. Curriculum vitae / Resume
3. Five professional references including name, address, phone number (mobile number if appropriate), and email address

Applications are accepted electronically ONLY at www.cu.edu/cu-careers.

Questions should be directed to: Dan Page daniel.page@cuanschutz.edu

Screening of Applications Begins

Immediately and continues until the position is filled. For best consideration, apply by August 1, 2025.

Anticipated Pay Range

The starting salary range (or hiring range) for this position has been established as HIRING RANGE:

$62,232.00 - $75,352.00 based on years of experience