Post-doctoral position in brain tumor microenvironment

Is the Job related to staff position within a Research Infrastructure? No

Offer Description

Glioblastoma (GBM) is the most aggressive primary brain tumor with poor prognosis. Increasing evidence indicates that extracellular vesicles (EVs) play a major role in tumor-microenvironment communication and contribute to cancer progression. Recent observations suggest that GBM cells interact with myelinated structures within the brain and that EV populations isolated from tumor-brain models display molecular signatures associated with myelin. However, the functional contribution of EV-mediated communication to glioblastoma invasion remains poorly understood.

The candidate will join Team 6 at the Nantes-Angers Cancer and Immunology Integrated Research Center (CRCI²NA) and contribute to a multidisciplinary project aimed at understanding the role of extracellular vesicles in GBM expansion. The project combines advanced cell culture systems, EV characterization, omics approaches and preclinical models to identify mechanisms by which tumor-derived EVs regulate their microenvironment and agressive behavior.

Where to apply

E-mail: julie.gavard@inserm.fr

Requirements

Research Field: Biological sciences » Biology

Education Level: PhD or equivalent

Skills/Qualifications

• Strong background in cancer biology, cell biology, molecular biology or extracellular vesicle research.
• Experience in mammalian cell culture and advanced cell biology techniques.
• Expertise in EV isolation and characterization methods
• Knowledge of tumor microenvironment biology.
• Communication skills and ability to work independently

Specific Requirements

Work involving human biological samples and animal models in accordance with institutional and regulatory guidelines.

Languages: ENGLISH

Level: Good

Research Field: Biological sciences » Biology

Years of Research Experience: 1 - 4

Work Location(s)

Number of offers available: 1

Company/Institute: CRCI2NA

Country: European Union

City: Nantes

Contact

City: Nantes

Website: https://www.univ-nantes.fr/

Website: https://nbidere.wixsite.com/soap

Street: Quai Moncousu

Postal Code: 44000