Is the Job related to staff position within a Research Infrastructure? No
Offer Description
Glioblastoma (GBM) is the most aggressive primary brain tumor with poor prognosis. Increasing evidence indicates that extracellular vesicles (EVs) play a major role in tumor-microenvironment communication and contribute to cancer progression. Recent observations suggest that GBM cells interact with myelinated structures within the brain and that EV populations isolated from tumor-brain models display molecular signatures associated with myelin. However, the functional contribution of EV-mediated communication to glioblastoma invasion remains poorly understood.
The candidate will join Team 6 at the Nantes-Angers Cancer and Immunology Integrated Research Center (CRCI²NA) and contribute to a multidisciplinary project aimed at understanding the role of extracellular vesicles in GBM expansion. The project combines advanced cell culture systems, EV characterization, omics approaches and preclinical models to identify mechanisms by which tumor-derived EVs regulate their microenvironment and agressive behavior.
Where to apply
E-mail: julie.gavard@inserm.fr
Requirements
Research Field: Biological sciences » Biology
Education Level: PhD or equivalent
Skills/Qualifications
- Strong background in cancer biology, cell biology, molecular biology or extracellular vesicle research.
- Experience in mammalian cell culture and advanced cell biology techniques.
- Expertise in EV isolation and characterization methods
- Knowledge of tumor microenvironment biology.
- Communication skills and ability to work independently
Specific Requirements
Work involving human biological samples and animal models in accordance with institutional and regulatory guidelines.
Languages: ENGLISH
Level: Good
Research Field: Biological sciences » Biology
Years of Research Experience: 1 - 4
Work Location(s)
Number of offers available: 1
Company/Institute: CRCI2NA
Country: European Union
City: Nantes
Contact
City: Nantes
Website: https://www.univ-nantes.fr/
Website: https://nbidere.wixsite.com/soap
Street: Quai Moncousu
Postal Code: 44000
