"Postdoctoral Research Associate"

About the role:

Age-related / adult-onset hearing loss (ARHL) is a complex neurodegenerative disease affecting millions of people worldwide. This is an exciting opportunity for a self-motivated and committed postdoctoral research associate to join the Nolan Hearing Lab and work on a research programme funded by the Wellcome Trust. The overarching objective is to understand the molecular mechanisms that underlie the long-known sex-differences in the maintenance of hearing over the life course and determine if sex-specific molecular pathways can be identified that are suitable as potential drug targets in ARHL.

The post-holder will work in the lab of Dr Lisa Nolan to support the development of a single-cell RNA-Seq pipeline for cochlear tissue that is suitable to translate to our various mouse models we currently have running in the lab. There will also be good opportunity to collaborate with other members of the Nolan lab working on aligned projects.

The post would suit somebody with solid experience of working with small rodents, mouse cochlear dissection and a strong interest in auditory neuroscience. Expertise in one or more of the following areas is also essential: cell culture/primary cell culture/single-cell or bulk RNA-Seq. An active or previous recipient of an Home Office Personal Licence is also highly desirable.

The post is based on Guy’s Campus and will benefit from further support from Dr Pawan Dhami, lead of the Genomics and Single Cell Laboratory at Guy’s Hospital.

This is a full-time post (35 hours per week), and you will be offered a fixed term contract for 12 months.

Research staff at King’s are entitled to at least 10 days per year (pro-rata) for professional development. This entitlement, from the Concordat to Support the Career Development of Researchers, applies to Postdocs, Research Assistants, Research and Teaching Technicians, Teaching Fellows and AEP equivalent up to and including grade 7. Visit the Centre for Research Staff Development for more information.

About you:

To be successful in this role, we are looking for candidates to have the following skills and experience:

Essential criteria

1. PhD qualified in Neuroscience or related subject area.
2. Solid expertise in cellular and/or molecular biology.
3. Significant previous experience with one or more of the following: cell culture/primary cell culture/single-cell or bulk RNA-Seq.
4. Previous experience with mouse cochlear dissections.
5. Excellent and demonstrated ability to thrive in a team.
6. Excellent organizational skills and meticulous attention to detail.
7. Ability to multitask, plan and prioritise workload to meet deadlines.

Desirable criteria

1. Home office personal licence.
2. Experience of communicating with people who have different types of hearing loss.
3. Experience of working with mice and / or managing mouse colonies.
4. FACS experience
5. Immuno-fluorescence analysis and confocal microscopy.

Further information:

We ask all candidates to submit a copy of their CV, and a supporting statement, detailing how they meet the essential criteria listed in the advert. If we receive a strong field of candidates, we may use the desirable criteria to choose our final shortlist, so please include your evidence against these where possible.

Grade and Salary: £45,031 - £49,871 per annum, including London Weighting Allowance

Job ID: 125926

Close Date: 30-Sep-2025

Contact Person: Dr Lisa Nolan

Contact Details: lisa.nolan@kcl.ac.uk