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Oxford Centre for Immuno-Oncology, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford, OX3 7DQ

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"Postdoctoral Research Scientist"

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Postdoctoral Research Scientist

Research Grade 7

20 March 2026, 12:00 midday

Location

Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford, OX3 7DQ

University of Oxford

Type

Full-time, Fixed-term until 30 April 2027

Salary

£39,424 - £47,779 p.a. (discretionary to £53,483)

Required Qualifications

PhD/DPhil in molecular immunology
MHC-E biochemistry/biology
T cell immunology
Virology
Growing CD8+ T cell clones
Isolating/sequencing T cell receptors
Lentiviral systems for TCR-transduced T cells
Excellent communication and publication skills

Research Areas

MHC-E peptide binding biochemistry
T cell immunology
Vaccine design
Virology
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Postdoctoral Research Scientist

Postdoctoral Research Scientist

Location: Oxford Centre for Immuno-Oncology, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford, OX3 7DQ

We are seeking to appoint a highly motivated Postdoctoral Research Scientist with relevant experience in MHC-E biochemistry/biology, T cell immunology and virology to progress the design of MHC-E based vaccine candidates. You will be working collaboratively alongside an existing team to support research currently centred on MHC-E peptide binding biochemistry, T cell immunology and vaccine design. You will manage your own academic research and administrative activities once initial training is satisfactorily completed, keeping daily records of work performed ensuring research is performed safely, legally and to the highest possible standards. This role also includes establishing and maintaining a good understanding of the research field by reading key reviews and research articles and collaborating in the preparation of scientific reports.

It is essential that you hold a PhD/DPhil (or be close to completion) in molecular immunology, ideally in the field of non-classical major histocompatibility complex E (MHC-E) and T cell recognition. You will be able to clearly demonstrate your evidence of growing CD8+ T cell clones, isolating/sequencing T cell receptors, and working with lentiviral systems to generate TCR-transduced T cells. Together with excellent communication skills, the ability to write for publication, present research proposals results, and represent the research group at meetings is required.

Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date. This position is offered full time on a fixed term contract until 30 April 2027 and is funded by the Gates Foundation.

Only applications received before 12 midday on Friday 20 March 2026 will be considered. Please quote 185182 on all correspondence.

Contact Person: Kristina Limbu
Contact Email: recruitment@ndm.ox.ac.uk
Vacancy ID: 185182
Closing Date & Time: 20-Mar-2026 12:00
Pay Scale: RESEARCH GRADE 7
Salary (£): Research Grade 7: £39,424 - £47,779 with a discretionary range to £53,483 p.a. (pro rata). This is inclusive of a pensionable Oxford University Weighting of £1,730 per year (pro rata)

185182 - Postdoctoral Research Scientist- JD.pdf (509.7 KB)

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Frequently Asked Questions

🎓What qualifications are required for the Postdoctoral Research Scientist role?

You must hold a PhD/DPhil (or be close to completion) in molecular immunology, ideally focusing on non-classical MHC-E and T cell recognition. Essential experience includes growing CD8+ T cell clones, isolating/sequencing T cell receptors (TCRs), and using lentiviral systems for TCR-transduced T cells. Excellent communication skills for publications and presentations are required. Learn more about thriving in postdoctoral research roles. Check Postdoc jobs for similar opportunities.

💰What is the salary and contract details?

The salary is Research Grade 7: £39,424 - £47,779 p.a. with a discretionary range to £53,483, including a pensionable Oxford University Weighting of £1,730 p.a. (pro rata). This is a full-time fixed-term contract until 30 April 2027, funded by the Gates Foundation. Explore university salaries for context.

📝How do I apply for this MHC-E Research Scientist position?

Applications must be made online before 12 midday on 20 March 2026. Upload a CV and supporting statement explaining how you meet each selection criterion with examples. Quote Vacancy ID: 185182. No other documents initially. Contact recruitment@ndm.ox.ac.uk for queries. Use our free resume template and cover letter template to prepare.

🔬What are the main responsibilities in this T cell immunology role?

You will progress MHC-E based vaccine candidates through MHC-E peptide binding biochemistry, T cell immunology, and vaccine design. Manage research and administrative activities, maintain records, ensure safety/compliance, read key literature, and collaborate on reports. Work collaboratively in the team at Oxford Centre for Immuno-Oncology. See tips for research assistant excellence, adaptable to postdocs.

🧬What research focus and skills are emphasized?

The role centers on MHC-E biochemistry/biology, T cell immunology, and virology for vaccine development. Key skills: evidence of CD8+ T cell clone growth, TCR isolation/sequencing, and lentiviral TCR transduction. Strong publication and presentation abilities required. Browse research jobs or clinical research jobs for related positions.

🌍Is visa sponsorship available for international applicants?

Visa sponsorship is not mentioned in the job posting. As a University of Oxford position, check eligibility directly via the contact email. International candidates should review UK visa requirements for postdoctoral research roles.
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