Primary Work Address: 4544 MSRB II, Dock #6, Ann Arbor, MI,
[contact details available in the full listing]
Current HHMI Employees, click here to apply via your Workday account.
The Bardwell lab at the University of Michigan is studying how cellular factors regulate protein homeostasis, and RNA structure, and how defects in these processes contribute to neurodegenerative disease. Our research focuses on proteins implicated in neurological disorders, including SERF family microproteins, the microtubule-associated protein tau, and the ALS-linked RNA-binding protein TDP-43. In particular, the lab's work focuses on how ribonucleoproteins affect the formation of non-canonical RNA structures called G4-quadruplexes which are involved in chromatin structure, protein folding and in amyloid formation which is involved in neurological diseases. Our research integrates genetic, molecular, cellular biology and structural biophysics to inform both basic biology and future therapeutic applications.
For more information, visit https://sites.lsa.umich.edu/bardwell-lab/
About the Role:
We are seeking a highly motivated and independent Postdoctoral Scientist to join our in-person, cross-disciplinary team. This role focuses on understanding the role of RNA binding proteins including microproteins using cell biological and NMR approaches. Projects aim to define how these proteins interact with RNA to affect its structure, how these interactions are disrupted in disease, and how those insights can guide translational research.
The position involves designing and executing experiments, overseeing undergraduate researchers, and collaborating closely with Dr. Bardwell and other lab members in a friendly, fast-paced, and discovery-driven environment.
Application Instructions
Please include the following items in one single PDF as part of your application. Cover Letter MUST be included for full consideration.
Current HHMI Employees, click here to apply via your Workday account.
The Bardwell lab at the University of Michigan is studying how cellular factors regulate protein homeostasis, and RNA structure, and how defects in these processes contribute to neurodegenerative disease. Our research focuses on proteins implicated in neurological disorders, including SERF family microproteins, the microtubule-associated protein tau, and the ALS-linked RNA-binding protein TDP-43. In particular, the lab's work focuses on how ribonucleoproteins affect the formation of non-canonical RNA structures called G4-quadruplexes which are involved in chromatin structure, protein folding and in amyloid formation which is involved in neurological diseases. Our research integrates genetic, molecular, cellular biology and structural biophysics to inform both basic biology and future therapeutic applications.
For more information, visit https://sites.lsa.umich.edu/bardwell-lab/
About the Role:
We are seeking a highly motivated and independent Postdoctoral Scientist to join our in-person, cross-disciplinary team. This role focuses on understanding the role of RNA binding proteins including microproteins using cell biological and NMR approaches. Projects aim to define how these proteins interact with RNA to affect its structure, how these interactions are disrupted in disease, and how those insights can guide translational research.
The position involves designing and executing experiments, overseeing undergraduate researchers, and collaborating closely with Dr. Bardwell and other lab members in a friendly, fast-paced, and discovery-driven environment.
Application Instructions
Please include the following items in one single PDF as part of your application. Cover Letter MUST be included for full consideration.
- A cover letter including a summary of your research experience,
your career goals, and your expertise in the relevant
field(s).
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