Research Assistant in Immunology

University of Oxford - Sir William Dunn School of Pathology

Location: South Parks Road, Oxford

We are seeking to appoint a talented and ambitious Research Assistant to join a dynamic and diverse group of researchers working on bacterial pathogenesis and innate immune signalling within the Thurston Group at the Sir William Dunn School of Pathology. The post holder will be responsible for supporting the teams’ goals in understanding the molecular mechanisms of Salmonella pathogenesis.

You will have the primary responsibility for supporting research projects on host pathogen interactions underpinning Salmonella virulence. You will be involved in diverse molecular and cellular work. At a molecular level, the work will involve protein expression and purification with associated in vitro assays. At a cellular level, cells infected with Salmonella will be analysed using a combination of immuno-fluorescence microscopy, flow cytometry and immunoblotting. CrispR cas9 is routinely used to create mammalian cell knockouts. RNAseq and proteomics-based approaches are also anticipated. Work will involve the preparation of mammalian cells stably expressing tagged proteins using lentiviral particles and transduction.

You should hold a first degree in biochemistry, biomedical sciences, or related field. You should have some molecular laboratory experience covering techniques such as molecular cloning, DNA transfection, and protein purification. You should be able to manage your own research and administrative activities and learn techniques from laboratory members. Experience working with bacteria/microbiology, protein production and purification or immunofluorescence microscopy are desirable but not essential.

This is a fixed-term appointment available for 2 years. If you are interested in this role, and have the skills and experience we are looking for, please apply online. You will be required to upload a CV and supporting statement as part of your online application. Informal inquiries can be sent to Professor Teresa Thurston via email teresa.thurston@path.ox.ac.uk.

The closing date for applications is 12:00 on Monday 23 February 2026. Interviews will be held as soon as possible thereafter.

At the Dunn School we are committed to supporting the professional and career development of our postdocs and research staff. To help them thrive and achieve their ambitions, we have created a comprehensive range of opportunities and initiatives designed to provide an exceptional launchpad for their future careers.