"Research Assistant-In vivo breast cancer prevention (GEMM) (Fixed Term)"

A Research Assistant position is available in the group of Prof. Walid T. Khaled at the Department of Pharmacology and Cambridge Stem Cell Institute, University of Cambridge.

This position is part of PreBRCATx, a major new project funded by the European Research Council (ERC), focused on developing therapeutic interventions to prevent hereditary breast cancer. Building on the Khaled Lab's expertise in tumour initiation and early transformation, this project aims to intercept breast cancer before it starts, with a particular focus on individuals carrying high-risk mutations in BRCA1, BRCA2, and PALB2. Through advanced single cell genomics, in vivo modelling, and immune profiling, the team will study early molecular and cellular changes that occur in high-risk breast tissue. The team will test the ability of known and near-clinical drugs to reverse or block these changes and ultimately aims to develop a preventive breast cancer vaccine for individuals with inherited predisposition. This role offers a rare opportunity to contribute to cancer interception science at the frontier of personalised prevention, with strong translational potential.

Requirements

To deliver on this exciting project the team is looking for an enthusiastic Research Assistant with a BSc degree in biological sciences that has demonstrable experience working with GEMMs. It is essential you hold an active PIL as you will be responsible for the maintenance of the GEMM colonies, performing in vivo experiments and the collection and analysis of the data. You will need to be an effective communicator, organised, and keep excellent and detailed records.

Fixed-term: The funds for this post are available for 24 months in the first instance (funded by ERC) subject to a probation period and performance review.

Please ensure that you upload a covering letter highlighting relevant experience to this project. You will also need to upload a CV and include the names of two referees as part of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application. Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

To apply online for this vacancy and to view further information about the role, please click the 'Apply' button above.

Informal enquiries should be addressed to Professor Walid T. Khaled (wtk22@cam.ac.uk).

For enquiries about the online application process, please contact the HR Team, hr@phar.cam.ac.uk

Please quote reference PL47143 on your application and in any correspondence about this vacancy.

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