Research Fellow

University of Birmingham - School of Biosciences

Location: Birmingham

Salary: £36,130 to £45,413 Grade 7

Hours: Full Time

Contract Type: Fixed-Term/Contract

Placed On: 7th July 2025

Closes: 31st August 2025

Job Ref: 105700

Full time starting salary is normally in the range £36,130 to £45,413 with potential progression once in post to £48,149

Contract Type: Fixed Term contract up to September 2027

Background

Our international group of highly motivated and interdisciplinary structural biologists is expanding! We are looking for a Research Fellow fascinated by the structural basis of molecular functions. You will study the mechanism of RNA acetylation, how post-translational modifications impact RNA structure and the molecular mechanisms by which acetylation of RNA impacts cellular functions. Your main research tool will be structural biology together with biochemical, biophysical and cellular assays. We offer unique access to first-class instrumentation for structural biology. At the national centre for biomolecular NMR spectroscopy in Birmingham (HWB-NMR), we host the best biomolecular NMR equipment available in the UK, comprising 1000 and 900 MHz spectrometers equipped with cryoprobes and MAS probes for both solution- and solid-state NMR, as well as an incoming 1.2 GHz spectrometer expected in spring 2025. At the Midlands Regional Cryo Electron Microscope Facility in Leicester, you will have access to a 300kV Titan Krios G3 cryo-electron microscope with a direct electron-detecting camera. We have BAG access to the synchrotron at DIAMOND for small angle scattering, X-ray crystallography and many more X-ray based techniques. Fully equipped biochemistry and molecular biology laboratories, as well as extensive equipment for in cellulo work and light microscopy are available. This interdisciplinary research environment will provide you with unique development opportunities.

Our globally-operating research group is embedded in a vibrant community of world-renowned scientists in the fields of genome biology, cancer research and microbiology. We believe in interdisciplinarity and we strive to integrate structural biology with functional studies in cells and whole organisms, as well as with drug design and molecular engineering.

If you are curious, motivated and ready for challenge to discover the rules of nature by biophysics, you can’t miss this opportunity!

Role Summary

• Work within specified research grants and projects and contribute to writing bids
• Operate within area of specialism
• Design and perform experiments
• Analyse and interpret research findings and results
• Contribute to generating funding
• Contribute to licensing or spin out deals with demonstrated commercial success (such as revenues, asset or company sales, IP generated) and/or public understanding of the discipline or similar

Person Specification

• First degree in Chemistry, Biochemistry or Biophysics (or in any closely related area) and normally, a higher degree relevant to research area (Structural biology, biochemistry and biophysics) or equivalent qualifications
• PhD (or near to completion) in relevant subject area (structural biology or biophysics)

Informal enquiries can be made to Professor Teresa Carlomagno, email: T.Carlomagno@bham.ac.uk

To download the full job description and details of this position and submit an electronic application online please click on the 'Apply' button above.