"Research Investigator Sr."

Job Description Summary

Design and execute experiments to elucidate the molecular structures of novel chemical entities (NCEs) and their radiolabeled counterparts.

Develop and optimize radiochemical methods for the radiolabeling of NCEs with various radioisotopes, including but not limited to F-18, Ga-68, Tc-99m, I-125, Lu-177, and Ac-225.

Optimize radiochemical yields through systematic experimentation and method refinement.

Establish and validate analytical quality control methods using techniques such as HPLC, TLC, and LC-MS for the characterization and assay of radiolabeled compounds and their precursors.

Conduct hands-on radiolabeling experiments in compliance with safety and regulatory standards.

Collaborate with interdisciplinary teams including synthetic chemists, pharmacologists, and imaging scientists to support research and development efforts.

Maintain detailed records of experimental procedures, data analysis, and results in laboratory notebooks and databases.

Job Responsibilities

• Design and execute experiments to elucidate the molecular structures of novel chemical entities (NCEs) and their radiolabeled counterparts.
• Develop and optimize radiochemical methods for the radiolabeling of NCEs with various radioisotopes, including but not limited to F-18, Ga-68, Tc-99m, I-125, Lu-177, and Ac-225.
• Optimize radiochemical yields through systematic experimentation and method refinement.
• Establish and validate analytical quality control methods using techniques such as HPLC, TLC, and LC-MS for the characterization and assay of radiolabeled compounds and their precursors.
• Conduct hands-on radiolabeling experiments in compliance with safety and regulatory standards.
• Collaborate with interdisciplinary teams including synthetic chemists, pharmacologists, and imaging scientists to support research and development efforts.
• Maintain detailed records of experimental procedures, data analysis, and results in laboratory notebooks and databases.
• Other duties as assigned

Position is contingent upon grant funding

Qualifications

• Doctor of Medicine, Doctor of Philosophy, and 5 to 7 years of postdoctoral experience is required.

Job Location

Philadelphia, Pennsylvania

Department / School

Perelman School of Medicine

Pay Range

$79,500.00 - $94,753.00 Annual Rate

Salary offers are made based on the candidate's qualifications, experience, skills, and education as they directly relate to the requirements of the position, and in alignment with salary ranges based on external market data for the job's level. Internal organization and peer data at Penn are also considered.

How to Apply

To apply, visit https://wd1.myworkdaysite.com/recruiting/upenn/careers-at-penn