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"Research Scientist 2"

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Research Scientist 2

Staff

May 10, 2026

Location

Cambridge

MIT

Type

Full-Time

Required Qualifications

PhD in Neuroscience/Neuroimmunology
4+ years postdoctoral experience
Human tissues & mouse models
Histopathological CNS analysis
Mucosal barrier permeability
In vivo disease models
8+ first-author publications
Grant writing & mentoring

Research Areas

Blood-brain barrier disruption
Infectious diseases
Neurocognitive dysfunction
Neuroinflammation
Gut permeability
Vascular cognitive impairment
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Research Scientist 2

RESEARCH SCIENTIST 2

Biological Engineering - The Griffith and Tal Research Groups, to lead the conceptualization, development, and execution of a project studying multi-barrier disruption (including blood-brain barrier and intestinal barrier) in the context of infectious diseases and investigate mechanistic links between barrier permeability and neurocognitive dysfunction. The research areas include molecular signaling and inflammatory mediators in blood-brain barrier regulation, vascular cognitive impairment, and infection-associated brain injury. Will manage multiple projects simultaneously; conceive and design experiments involving both human samples and mouse models; serve as a point person to interact with external collaborators; and take a leading role in preparing grant proposals, manuscripts, and patent applications.

Job Requirements

REQUIRED: PhD in Neuroscience, Neuroimmunology, or a related field; and a minimum of four years of postdoctoral experience in neuroimmunology, cardiovascular disease, gut permeability, mucosal barriers, and infectious diseases; extensive experience with both human tissues and mouse models of disease, including chronic Lyme disease mouse model, autoimmunity, and models of viral infection; extensive experience with histopathological and imaging analysis of CNS tissues, immune response, axonal damage, and neuroinflammation; experience analyzing several mucosal surfaces in the body (gut, vaginal/uterine, etc), including barrier permeability, inflammatory markers, and tissue damage; proficiency in developing and maintaining different in vivo models for autoimmune, cardiovascular, ageing and infectious diseases models; skilled in administration of therapeutics via tail vein (IV), intraperitoneal, intramuscular, oral gavage, and subcutaneous injections; experience designing multiplex panels; a proven track record of scholarly success with at least 8 publications as first author in these relevant fields; demonstrated experience in mentoring students (graduate/undergraduate) and supervising technical staff; significant experience in grant writing, funding strategy development, and proposal creation; and experience with collaborative interdisciplinary research.

This is a 1-year position with the possibility of an extension, subject to funding availability.

  • Job Number: 25549
  • Functional Area: Research - Scientific
  • Department: Department of Biological Engineering
  • School Area: Engineering
  • Employment Type: Full-Time
  • Employment Category: Exempt
  • Visa Sponsorship Available: No

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Frequently Asked Questions

🎓What qualifications are required for the Research Scientist 2 position?

Candidates must hold a PhD in Neuroscience, Neuroimmunology, or related field with at least four years of postdoctoral experience in neuroimmunology, cardiovascular disease, gut permeability, mucosal barriers, and infectious diseases. Extensive hands-on experience with human tissues and mouse models (e.g., chronic Lyme, autoimmunity, viral infection) is essential, including histopathological analysis of CNS tissues, immune responses, and barrier permeability across mucosal surfaces. A proven track record with 8+ first-author publications, mentoring experience, and grant writing is required. Review postdoc success tips for preparation.

🔬What research responsibilities will the role involve?

Lead conceptualization, development, and execution of projects on multi-barrier disruption (e.g., blood-brain barrier, intestinal barrier) in infectious diseases, investigating links to neurocognitive dysfunction. Manage multiple projects, design experiments with human samples and mouse models, interact with collaborators, and lead grant proposals, manuscripts, and patent applications. Focus areas include molecular signaling, inflammatory mediators, vascular cognitive impairment, and infection-associated brain injury. Explore research jobs for similar opportunities.

🧪What technical skills are needed for in vivo models and analysis?

Proficiency in developing/maintaining in vivo models for autoimmune, cardiovascular, aging, and infectious diseases. Skilled in therapeutic administration via tail vein IV, IP, IM, oral gavage, subcutaneous injections. Experience with histopathological and imaging analysis of CNS tissues, immune response, axonal damage, neuroinflammation, and multiplex panels. Analyze mucosal surfaces (gut, vaginal/uterine) for barrier permeability, inflammatory markers, and tissue damage. Check research assistant skills for related expertise.

📅Is visa sponsorship available, and what is the employment duration?

Visa sponsorship is not available. This is a 1-year full-time exempt position with possibility of extension subject to funding. Located in Cambridge, MA at MIT's Department of Biological Engineering. For more on postdoc and research roles, visit our listings.

📝How to apply and prepare for this neuroimmunology research role?

Apply via job number 25549 before the expiration date of May 10, 2026. Highlight your interdisciplinary collaborative experience, scholarly success, and skills in neuroimmunology mouse models. Prepare a CV emphasizing publications and grants. Use our free resume template and cover letter template to strengthen your application.

🚀What career development opportunities does this position offer?

Significant experience in grant writing, funding strategy, manuscript preparation, and patents. Lead role in projects, mentor students and staff, and collaborate interdisciplinary. Ideal for advancing in Biological Engineering and neuroimmunology research. See faculty jobs for next steps.
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