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CalTech - California Institute of Technology

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Pasadena, CA

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"Research Scientist"

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Research Scientist

Staff / Administration

May 15, 2026

Location

Pasadena, CA

California Institute of Technology (Caltech)

Type

Full-time Temporary

Salary

$79,700 - $120,000 Per Year

Required Qualifications

PhD in Immunology
5+ years experience
Mammalian cell culture
ELISA, Western blots, flow cytometry
Excellent communication skills

Research Areas

Autoimmune disease
Antigen-specific immune tolerance
Translational immunology
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Research Scientist

Position Description

Research Scientist

Job Category
Fulltime Temporary

ExemptOvertimeEligible
Exempt

Benefits Eligible
Benefit Based

Apply Now

Caltech is a world-renowned science and engineering institute that marshals some of the world's brightest minds and most innovative tools to address fundamental scientific questions. We thrive on finding and cultivating talented people who are passionate about what they do. Join us and be a part of the diverse Caltech community.


Job Summary

The Mayo Laboratory at the California Institute of Technology (Caltech) seeks a highly motivated Research Scientist with a PhD and postdoctoral training in immunology to advance the lab’s research programs focused on autoimmune disease, antigen-specific immune tolerance, and translational immunology. This position will conduct research that follows from the recent Olson et al. PNAS publication (doi: 10.1073/pnas.2501046122).

Essential Job Duties

  • Organize, plan, and conduct experiments to study and investigate scientific problems and engineering challenges in immunology.
  • Drive data generation for high-impact publications and grant applications.
  • Analyze and present data at lab meetings, conferences, and in manuscripts.
  • Collaborate with other labs, core facilities, academic institutions, and companies.
  • Mentor graduate students, postdoctoral fellows, and/or research staff as appropriate.
  • Partner with Principal Investigator on initiating, writing, and/or submitting grant proposals.

Basic Qualifications

  • PhD in Immunology or a closely related discipline.
  • Must have 5 years of relevant experience (including time spent in predoctoral and postdoctoral training).
  • Demonstrated expertise with mammalian cell culture.
  • Demonstrated competence with techniques such as ELISA, Western blots, and flow cytometry.
  • Excellent analytical, organizational, and written and verbal communication skills.

Preferred Qualifications

  • Postdoctoral research experience with a strong publication record.
  • Demonstrated expertise in cellular and molecular immunology.
  • Demonstrated expertise in murine or other in vivo models of immune function or autoimmunity.
  • Experience with autoimmune disease, immune tolerance, or chronic inflammation.
  • Familiarity with translational and/or preclinical research concepts.
  • Interest in therapeutic modalities (e.g., biologics, nanoparticles, gene-based approaches).

Required Documents

  • Resume

Hiring Range

$79,700 - $120,000 Per Year

The salary of the finalist(s) selected for this role will be set based on a variety of factors, including but not limited to, internal equity, experience, education, specialty and training.

As one of the largest employers in Pasadena, CA, Caltech is committed to providing comprehensive benefits to eligible employees and their eligible dependents. Our benefits package includes competitive compensation, health, dental, and vision insurance, retirement savings plans, generous paid time off (vacation, holidays, sick time, parental leave, bereavement, etc.), tuition reimbursement, and more. Non-benefit eligible employees will have access to some benefits such as onsite counseling and sick time. Learn more about our benefits and staff perks.

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Frequently Asked Questions

🎓What are the basic qualifications for this Research Scientist role at Caltech?

Candidates must hold a PhD in Immunology or related field with 5 years of relevant experience, including pre/postdoc training. Required skills include mammalian cell culture, ELISA, Western blots, and flow cytometry. Excellent analytical and communication skills are essential. Preferred: postdoctoral experience and expertise in autoimmune disease or immune tolerance. Explore more on research jobs or postdoc success tips.

🔬What research duties will the Research Scientist handle in Mayo Laboratory?

Key duties: Organize and conduct immunology experiments, generate data for high-impact publications and grants, analyze/present findings, collaborate with labs/companies, mentor students/postdocs, and assist with grant proposals. Focus aligns with recent PNAS publication on autoimmune disease and antigen-specific immune tolerance. See related clinical research jobs.

💰What is the salary and benefits for this Caltech Immunology position?

Salary range: $79,700 - $120,000 per year, based on experience. Benefit Based package includes health/dental/vision insurance, retirement savings, generous PTO, tuition reimbursement, and more. Non-benefit employees get counseling/sick time. Details at Caltech benefits page. Compare with professor salaries.

📝How do I apply for the Research Scientist job in Pasadena, CA?

Submit a resume via the official link: Apply Now. Position is Full-time Temporary, exempt. Deadline: May 15, 2026. Tailor your application for Caltech research roles. Free resources: resume template and cover letter template.

🧪What preferred skills are ideal for translational immunology at Caltech?

Preferred: Postdoctoral experience with publications, expertise in cellular/molecular immunology, in vivo models (murine/autoimmunity), autoimmune disease, immune tolerance, chronic inflammation, and translational/preclinical research. Interest in therapeutics like biologics/nanoparticles. Check research assistant advice or similar jobs.

🚀Is this Research Scientist role suitable for postdocs seeking staff positions?

Yes, ideal for postdocs with immunology PhD and strong publication record transitioning to staff research. Involves independent experiments, collaboration, mentoring, and grants in Mayo Laboratory. No teaching load. Learn to thrive via postdoc success guide.
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