Research Specialist B (Department of Obstetrics and Gynecology)
Job Description Summary
The Nasioudis Lab in the PSOM Department of Obstetrics and Gynecology, is a newly established research laboratory dedicated to advancing translational research in gynecologic oncology, with a focus on developing innovative therapeutic strategies for gynecological malignancies.
We are seeking an experienced, dedicated, and detail-oriented Research Specialist to join this dynamic team. This position offers a unique opportunity to contribute to cutting-edge cancer research while gaining hands-on experience in both laboratory and preclinical methodologies. The successful candidate will support a wide range of experimental work, including cell culture, organoid modeling, and mouse model studies, while also assisting in lab setup and operations.
This role is ideal for individuals who are passionate about biomedical research, thrive in collaborative environments, and are eager to expand their technical and scientific skillsets.
Job Responsibilities
- Design new experiments and contribute to research publications and presentations
- Maintain and passage human cell cultures
- Generate, passage, store, and treat patient-derived organoid models
- Assist in the management of a mouse colony, including care, drug administration via oral gavage, and dosing schedules
- Support surgical procedures to develop patient-derived xenografts (PDX)
- Measure tumor size in mice using palpation and ultrasound
- Perform necropsy and bio-bank tissue samples
- Assist with processing formalin-fixed paraffin-embedded (FFPE) tissue samples
- Participate in lab management, including ordering, organizing, and maintaining reagents, equipment, and protocols
- Provide scientific and technical guidance for ongoing projects
- Maintain organized laboratory records and ensure compliance with safety protocols
- Perform other duties as assigned
Position contingent upon continued funding
Qualifications
- Bachelor's degree and 1-3 years of laboratory experience or equivalent combination of education and experience
The ideal candidate will reflect the following experience:
- Experience working with mice in a rodent barrier facility
- Familiarity with drug administration via oral gavage and survival surgeries (preferred)
- Experience with necropsy and tissue banking (preferred)
- Experience generating and culturing patient-derived organoids (preferred)
- Proficiency in tissue culture, including human primary cells (preferred)
- Familiarity with basic laboratory techniques such as Western blotting and flow cytometry (preferred)
- Strong organizational skills and attention to detail
- Ability to maintain accurate and organized laboratory data
- Effective communication and teamwork skills
- Flexibility with work hours and ability to multitask in a fast-paced environment
Job Location
Philadelphia, Pennsylvania
Department / School
Perelman School of Medicine
Pay Range
$50,000.00 - $57,335.40 Annual Rate
Salary offers are made based on the candidate's qualifications, experience, skills, and education as they directly relate to the requirements of the position, and in alignment with salary ranges based on external market data for the job's level. Internal organization and peer data at Penn are also considered.
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