UTS - Temporary GMP Manufacturing Technician at UNC Chapel Hill

Essential Job Duties

The Advanced Cellular Therapeutics (ACT) Facility is a Good Manufacturing Practices (GMP) facility focused on expansion and manipulation of human cells for clinical phase 1 applications, specifically including applications involving chimeric antigen receptor (CAR) T cells. The ACT Facility also manufactures Master Cell Banks (MCBs) used in the production of clinical grade gamma retrovirus vector for use in CAR T clinical trials.

Department Required Skills

• Perform cell culture activities within an ISO 7 clean room environment in compliance with Good Manufacturing Practices (GMP).
• Work aseptically in a Biological Safety Cabinet (BSC) to ensure product integrity and prevent contamination.
• Execute cell counting, assess cell viability, and perform related in-process testing to support the manufacturing of patient-specific cellular therapy products.
• Follow established Standard Operating Procedures (SOPs) and batch records accurately, documenting all activities in accordance with GMP requirements.
• Make routine manufacturing decisions within defined procedures to support timely and compliant production of patient products.
• Demonstrate sound judgment by recognizing when to seek guidance, escalate issues, or request support from manufacturing leadership or quality personnel when questions or deviations arise.
• Collaborate effectively with cross-functional teams to ensure safe, consistent, and high-quality manufacturing operations.