Corneel Heymans (1920) - Nobel Prize in Physiology or Medicine in 1938 for his discovery of the role played by the sinus and aortic mechanisms in the regulation of respiration.
Maurice Maeterlinck (1885) - Nobel Prize in Literature in 1911 for his dramatic works.
Leo Apostel (1952) - Philosopher and professor at the Universiteit Gent, known for his work in the philosophy of science.
Jean-Marie Pfaff (1976) - Former professional football goalkeeper, considered one of the best in the world during his career.
Frank De Winne (1984) - European Space Agency astronaut, the first European to command a space mission.