Rate My Professor James Bayrer

Bayrer's research utilizes human intestinal organoids and animal models to investigate how the intestinal epithelium, the body's largest sensory and endocrine organ, senses and responds to regular and inflammatory stimuli. His work identifies molecular pathways to promote intestinal wound healing and modulate signals contributing to visceral pain syndromes, with applications to diseases like inflammatory bowel disease. Key publications include "Gut enterochromaffin cells drive visceral pain and anxiety" (Nature, 2023), "Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways" (Cell, 2017), "LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival" (Nature Communications, 2018), "A thermogenic fat-epithelium cell axis regulates intestinal disease tolerance" (Proceedings of the National Academy of Sciences, 2020), "Advances in Enteric Neurobiology: The 'Brain' in the Gut in Health and Disease" (Journal of Neuroscience, 2018), and "Intestinal Organoids: New Frontiers in the Study of Intestinal Disease and Physiology" (Journal of Pediatric Gastroenterology and Nutrition, 2017). Bayrer has earned major awards including the Society for Pediatric Research New Member Outstanding Science Award (2024), National Academy of Sciences Kavli Fellow (2024), Mayo Clinic Kelsey Family Named Professor Lectureship (2024), Society for Pediatric Research Elected Member (2023), American Gastroenterological Association Early Career Investigator Certificate of Recognition (2018), and NASPGHAN Young Faculty Investigator Research Award (2015).