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Rate My Professor Simone Di Giovanni

Imperial College London

Ratings & reviews

5.05/4/2026

Makes every class a memorable experience.

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About Simone

Professor Simone Di Giovanni, MD, PhD, holds the James W Harnett Chair in Restorative Neuroscience in the Department of Brain Sciences within the Faculty of Medicine at Imperial College London. His academic career includes prior affiliation with the Hertie Institute for Clinical Brain Research at the University of Tübingen, where he contributed to neuroscience research. Di Giovanni leads a research group focused on the molecular, cellular, and epigenetic mechanisms governing axon regeneration and functional recovery after central nervous system trauma, with a particular emphasis on spinal cord injuries. His investigations delve into critical processes such as metabolic reprogramming, including glycolytic shunts through the pentose phosphate pathway that hallmark successful regeneration, the influence of gut metabolites like indole-3-propionate on nerve repair, and the roles of immune cells, including macrophages releasing glutamate to excite muscle spindles and cytotoxic T cells disrupting myeloid responses during aging.